Viral Etiological Agent(s) of Respiratory Tract Infections in Symptomatic Individuals during the Second Wave of COVID-19 Pandemic: A Single Drive-Thru Mobile Collection Site Study
One of the tools to contain the SARS-CoV-2 pandemic was to increase the number of performed tests and to improve the access to diagnostics. To this effect, mobile collection sites (MCSs) were established. This study was performed on samples collected at the MCS between November 2020 and March 2021....
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
|
| Series: | Pathogens |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-0817/11/4/475 |
| _version_ | 1827599735546970112 |
|---|---|
| author | Aleksandra Kozinska Karolina Wegrzynska Magdalena Komiazyk Jaroslaw Walory Izabela Wasko Anna Baraniak |
| author_facet | Aleksandra Kozinska Karolina Wegrzynska Magdalena Komiazyk Jaroslaw Walory Izabela Wasko Anna Baraniak |
| author_sort | Aleksandra Kozinska |
| collection | DOAJ |
| description | One of the tools to contain the SARS-CoV-2 pandemic was to increase the number of performed tests and to improve the access to diagnostics. To this effect, mobile collection sites (MCSs) were established. This study was performed on samples collected at the MCS between November 2020 and March 2021. We aimed to confirm/exclude SARS-CoV-2, differentiate SARS-CoV-2 variants, and detect other respiratory pathogens. SARS-CoV-2 and other respiratory viruses were identified by RT-qPCRs. A total of 876 (46.35%) SARS-CoV-2 positive specimens in the diagnostic tests were identified. The wild-type variant was determined in 667 (76.14%) samples; the remaining 209 (23.86%) samples specimens were identified as Alpha variant. A total of 51 (5.6%) non-SARS-CoV-2 cases were detected in retrospective studies. These accounted for 33 cases of mono-infection including rhinovirus (RV), human adenovirus (HAdV), human metapneumovirus (HMPV), enterovirus (EV), and influenza virus, and 18 cases of co-infection (SARS-CoV-2 with RV or HAdV or HMPV, and RV with EV). Our research shows that the results obtained from the MCS have value in epidemiological studies, reflecting national trends on a micro scale. Although the spread of COVID-19 is a major public health concern, SARS-CoV-2 is not the only pathogen responsible for respiratory infections. |
| first_indexed | 2024-03-09T04:19:39Z |
| format | Article |
| id | doaj.art-b5f179b80e8246e89970a75680a36811 |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-09T04:19:39Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-b5f179b80e8246e89970a75680a368112023-12-03T13:49:11ZengMDPI AGPathogens2076-08172022-04-0111447510.3390/pathogens11040475Viral Etiological Agent(s) of Respiratory Tract Infections in Symptomatic Individuals during the Second Wave of COVID-19 Pandemic: A Single Drive-Thru Mobile Collection Site StudyAleksandra Kozinska0Karolina Wegrzynska1Magdalena Komiazyk2Jaroslaw Walory3Izabela Wasko4Anna Baraniak5Department of Biomedical Research, National Medicines Institute, 00-725 Warsaw, PolandDepartment of Biomedical Research, National Medicines Institute, 00-725 Warsaw, PolandDepartment of Biomedical Research, National Medicines Institute, 00-725 Warsaw, PolandDepartment of Biomedical Research, National Medicines Institute, 00-725 Warsaw, PolandDepartment of Biomedical Research, National Medicines Institute, 00-725 Warsaw, PolandDepartment of Biomedical Research, National Medicines Institute, 00-725 Warsaw, PolandOne of the tools to contain the SARS-CoV-2 pandemic was to increase the number of performed tests and to improve the access to diagnostics. To this effect, mobile collection sites (MCSs) were established. This study was performed on samples collected at the MCS between November 2020 and March 2021. We aimed to confirm/exclude SARS-CoV-2, differentiate SARS-CoV-2 variants, and detect other respiratory pathogens. SARS-CoV-2 and other respiratory viruses were identified by RT-qPCRs. A total of 876 (46.35%) SARS-CoV-2 positive specimens in the diagnostic tests were identified. The wild-type variant was determined in 667 (76.14%) samples; the remaining 209 (23.86%) samples specimens were identified as Alpha variant. A total of 51 (5.6%) non-SARS-CoV-2 cases were detected in retrospective studies. These accounted for 33 cases of mono-infection including rhinovirus (RV), human adenovirus (HAdV), human metapneumovirus (HMPV), enterovirus (EV), and influenza virus, and 18 cases of co-infection (SARS-CoV-2 with RV or HAdV or HMPV, and RV with EV). Our research shows that the results obtained from the MCS have value in epidemiological studies, reflecting national trends on a micro scale. Although the spread of COVID-19 is a major public health concern, SARS-CoV-2 is not the only pathogen responsible for respiratory infections.https://www.mdpi.com/2076-0817/11/4/475COVID-19SARS-CoV-2variants of SARS-CoV-2respiratory virusesco-infection |
| spellingShingle | Aleksandra Kozinska Karolina Wegrzynska Magdalena Komiazyk Jaroslaw Walory Izabela Wasko Anna Baraniak Viral Etiological Agent(s) of Respiratory Tract Infections in Symptomatic Individuals during the Second Wave of COVID-19 Pandemic: A Single Drive-Thru Mobile Collection Site Study Pathogens COVID-19 SARS-CoV-2 variants of SARS-CoV-2 respiratory viruses co-infection |
| title | Viral Etiological Agent(s) of Respiratory Tract Infections in Symptomatic Individuals during the Second Wave of COVID-19 Pandemic: A Single Drive-Thru Mobile Collection Site Study |
| title_full | Viral Etiological Agent(s) of Respiratory Tract Infections in Symptomatic Individuals during the Second Wave of COVID-19 Pandemic: A Single Drive-Thru Mobile Collection Site Study |
| title_fullStr | Viral Etiological Agent(s) of Respiratory Tract Infections in Symptomatic Individuals during the Second Wave of COVID-19 Pandemic: A Single Drive-Thru Mobile Collection Site Study |
| title_full_unstemmed | Viral Etiological Agent(s) of Respiratory Tract Infections in Symptomatic Individuals during the Second Wave of COVID-19 Pandemic: A Single Drive-Thru Mobile Collection Site Study |
| title_short | Viral Etiological Agent(s) of Respiratory Tract Infections in Symptomatic Individuals during the Second Wave of COVID-19 Pandemic: A Single Drive-Thru Mobile Collection Site Study |
| title_sort | viral etiological agent s of respiratory tract infections in symptomatic individuals during the second wave of covid 19 pandemic a single drive thru mobile collection site study |
| topic | COVID-19 SARS-CoV-2 variants of SARS-CoV-2 respiratory viruses co-infection |
| url | https://www.mdpi.com/2076-0817/11/4/475 |
| work_keys_str_mv | AT aleksandrakozinska viraletiologicalagentsofrespiratorytractinfectionsinsymptomaticindividualsduringthesecondwaveofcovid19pandemicasingledrivethrumobilecollectionsitestudy AT karolinawegrzynska viraletiologicalagentsofrespiratorytractinfectionsinsymptomaticindividualsduringthesecondwaveofcovid19pandemicasingledrivethrumobilecollectionsitestudy AT magdalenakomiazyk viraletiologicalagentsofrespiratorytractinfectionsinsymptomaticindividualsduringthesecondwaveofcovid19pandemicasingledrivethrumobilecollectionsitestudy AT jaroslawwalory viraletiologicalagentsofrespiratorytractinfectionsinsymptomaticindividualsduringthesecondwaveofcovid19pandemicasingledrivethrumobilecollectionsitestudy AT izabelawasko viraletiologicalagentsofrespiratorytractinfectionsinsymptomaticindividualsduringthesecondwaveofcovid19pandemicasingledrivethrumobilecollectionsitestudy AT annabaraniak viraletiologicalagentsofrespiratorytractinfectionsinsymptomaticindividualsduringthesecondwaveofcovid19pandemicasingledrivethrumobilecollectionsitestudy |