A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty
Background: As much as there are unmet needs for brief frailty assessment in patients with chronic obstructive pulmonary disease (COPD), the lack of a simplified and comprehensive dyspnea evaluation system that focuses on the patients’ perceptions of dyspnea and their COPD living disabilities remain...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-11-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/11/3580 |
| _version_ | 1797548632775327744 |
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| author | Keiji Oishi Kazuto Matsunaga Misa Harada Junki Suizu Keita Murakawa Ayumi Chikumoto Yuichi Ohteru Kazuki Matsuda Sho Uehara Kazuki Hamada Shuichiro Ohata Yoriyuki Murata Yoshikazu Yamaji Maki Asami-Noyama Nobutaka Edakuni Tomoyuki Kakugawa Tsunahiko Hirano |
| author_facet | Keiji Oishi Kazuto Matsunaga Misa Harada Junki Suizu Keita Murakawa Ayumi Chikumoto Yuichi Ohteru Kazuki Matsuda Sho Uehara Kazuki Hamada Shuichiro Ohata Yoriyuki Murata Yoshikazu Yamaji Maki Asami-Noyama Nobutaka Edakuni Tomoyuki Kakugawa Tsunahiko Hirano |
| author_sort | Keiji Oishi |
| collection | DOAJ |
| description | Background: As much as there are unmet needs for brief frailty assessment in patients with chronic obstructive pulmonary disease (COPD), the lack of a simplified and comprehensive dyspnea evaluation system that focuses on the patients’ perceptions of dyspnea and their COPD living disabilities remains a major challenge. We developed patient-reported outcome measures for dyspnea-related behavior and activity limitation (PROMs-D), which consisted of the Activity-limit Dyspnea Scale (ADS) and Self-Limit Dyspnea Scale (SDS), while investigated the usefulness of PROMs-D in identifying frailty. Methods: We administered PROMs-D and frailty status evaluations in 128 outpatients. Results: We classified 30 (23.4%), 50 (39.0%), and 48 (37.5%) patients as robust, prefrail, and frail, respectively. There was a positive correlation between SDS and ADS (<i>ρ</i> = 0.67, <i>p</i> < 0.001), and both ADS and SDS had high accuracies for detecting frailty (AUC, 0.82 and 0.78, respectively). Moreover, a PROMs-D score that consisted of the sum of ADS and SDS was more effective in stratifying frailty (cutoff value, 2; AUC, 0.85; sensitivity, 60%; specificity, 95%). Conclusions: PROMs-D could be used as the first step for frailty screening in patients with COPD, and we propose the importance of capturing the troublesome nature of living behaviors due to dyspnea in daily clinical practice. |
| first_indexed | 2024-03-10T15:03:21Z |
| format | Article |
| id | doaj.art-b5f1c3d7ab6949be9b225f374586a88a |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T15:03:21Z |
| publishDate | 2020-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-b5f1c3d7ab6949be9b225f374586a88a2023-11-20T20:02:13ZengMDPI AGJournal of Clinical Medicine2077-03832020-11-01911358010.3390/jcm9113580A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and FrailtyKeiji Oishi0Kazuto Matsunaga1Misa Harada2Junki Suizu3Keita Murakawa4Ayumi Chikumoto5Yuichi Ohteru6Kazuki Matsuda7Sho Uehara8Kazuki Hamada9Shuichiro Ohata10Yoriyuki Murata11Yoshikazu Yamaji12Maki Asami-Noyama13Nobutaka Edakuni14Tomoyuki Kakugawa15Tsunahiko Hirano16Department of Medicine and Clinical Science, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Medicine and Clinical Science, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Pulmonology and Gerontology Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanDepartment of Respiratory Medicine and Infectious Disease, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, JapanBackground: As much as there are unmet needs for brief frailty assessment in patients with chronic obstructive pulmonary disease (COPD), the lack of a simplified and comprehensive dyspnea evaluation system that focuses on the patients’ perceptions of dyspnea and their COPD living disabilities remains a major challenge. We developed patient-reported outcome measures for dyspnea-related behavior and activity limitation (PROMs-D), which consisted of the Activity-limit Dyspnea Scale (ADS) and Self-Limit Dyspnea Scale (SDS), while investigated the usefulness of PROMs-D in identifying frailty. Methods: We administered PROMs-D and frailty status evaluations in 128 outpatients. Results: We classified 30 (23.4%), 50 (39.0%), and 48 (37.5%) patients as robust, prefrail, and frail, respectively. There was a positive correlation between SDS and ADS (<i>ρ</i> = 0.67, <i>p</i> < 0.001), and both ADS and SDS had high accuracies for detecting frailty (AUC, 0.82 and 0.78, respectively). Moreover, a PROMs-D score that consisted of the sum of ADS and SDS was more effective in stratifying frailty (cutoff value, 2; AUC, 0.85; sensitivity, 60%; specificity, 95%). Conclusions: PROMs-D could be used as the first step for frailty screening in patients with COPD, and we propose the importance of capturing the troublesome nature of living behaviors due to dyspnea in daily clinical practice.https://www.mdpi.com/2077-0383/9/11/3580dyspneaPROMsactivity-limitself-limitfrailty |
| spellingShingle | Keiji Oishi Kazuto Matsunaga Misa Harada Junki Suizu Keita Murakawa Ayumi Chikumoto Yuichi Ohteru Kazuki Matsuda Sho Uehara Kazuki Hamada Shuichiro Ohata Yoriyuki Murata Yoshikazu Yamaji Maki Asami-Noyama Nobutaka Edakuni Tomoyuki Kakugawa Tsunahiko Hirano A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty Journal of Clinical Medicine dyspnea PROMs activity-limit self-limit frailty |
| title | A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty |
| title_full | A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty |
| title_fullStr | A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty |
| title_full_unstemmed | A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty |
| title_short | A New Dyspnea Evaluation System Focusing on Patients’ Perceptions of Dyspnea and Their Living Disabilities: The Linkage between COPD and Frailty |
| title_sort | new dyspnea evaluation system focusing on patients perceptions of dyspnea and their living disabilities the linkage between copd and frailty |
| topic | dyspnea PROMs activity-limit self-limit frailty |
| url | https://www.mdpi.com/2077-0383/9/11/3580 |
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