Glycyrrhizin through liquorice intake modulates ACE2 and HMGB1 levels-A pilot study in healthy individuals with implications for COVID-19 and ARDS.

<h4>Background</h4>Glycyrrhizin, an active component of liquorice root extract, exhibits antiviral and immunomodulatory properties by direct inhibition of the pro-inflammatory alarmin HMGB1 (High-mobility group box 1).<h4>Objective</h4>The aim of this study was to explore the...

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Bibliographic Details
Main Authors: Felix Buder, Simina-Ramona Selejan, Mathias Hohl, Michael Kindermann, Christian Herr, Philipp M Lepper, Robert Bals, Bernd Salzberger, Felix Mahfoud, Michael Böhm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0275181