Neurostimulation for the treatment of functional neurological disorder: A systematic review

Functional Neurological Disorder (FND), also known as conversion disorder, is characterized by neurological symptoms that are incompatible with any known structural disorder and best explained by a biopsychosocial model. Evidence-based treatments for FND are limited, with cognitive behavioral therap...

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Main Authors: Irene Gonsalvez, Primavera Spagnolo, Barbara Dworetzky, Gaston Baslet
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Epilepsy & Behavior Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589986421000757
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author Irene Gonsalvez
Primavera Spagnolo
Barbara Dworetzky
Gaston Baslet
author_facet Irene Gonsalvez
Primavera Spagnolo
Barbara Dworetzky
Gaston Baslet
author_sort Irene Gonsalvez
collection DOAJ
description Functional Neurological Disorder (FND), also known as conversion disorder, is characterized by neurological symptoms that are incompatible with any known structural disorder and best explained by a biopsychosocial model. Evidence-based treatments for FND are limited, with cognitive behavioral therapy (CBT) and physiotherapy being the most effective interventions [1]. In recent years, functional neuroimaging studies have provided robust evidence of alterations in activity and connectivity in multiple brain networks in FND. This body of evidence suggests that neurocircuitry-based interventions, such as non-invasive brain stimulation techniques (NIBS), may also represent an effective therapeutic option for patients with FND.In this systematic review, we outline the current state of knowledge of NIBS in FND, and discuss limitations and future directions that may help establish the efficacy of NIBS as a therapeutic option for FND.
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spelling doaj.art-b5f8f831bd8d418092bf08f747a1413a2022-12-22T04:09:03ZengElsevierEpilepsy & Behavior Reports2589-98642021-01-0116100501Neurostimulation for the treatment of functional neurological disorder: A systematic reviewIrene Gonsalvez0Primavera Spagnolo1Barbara Dworetzky2Gaston Baslet3Department of Psychiatry, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; Corresponding author.Mary Horrigan Connors Center for Women's Health & Gender Biology, Department of Psychiatry, Brigham and Women Hospital, Harvard Medical School, Boston, MA 02115, USADepartment of Neurology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USADepartment of Psychiatry, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USAFunctional Neurological Disorder (FND), also known as conversion disorder, is characterized by neurological symptoms that are incompatible with any known structural disorder and best explained by a biopsychosocial model. Evidence-based treatments for FND are limited, with cognitive behavioral therapy (CBT) and physiotherapy being the most effective interventions [1]. In recent years, functional neuroimaging studies have provided robust evidence of alterations in activity and connectivity in multiple brain networks in FND. This body of evidence suggests that neurocircuitry-based interventions, such as non-invasive brain stimulation techniques (NIBS), may also represent an effective therapeutic option for patients with FND.In this systematic review, we outline the current state of knowledge of NIBS in FND, and discuss limitations and future directions that may help establish the efficacy of NIBS as a therapeutic option for FND.http://www.sciencedirect.com/science/article/pii/S2589986421000757FNDFunctional seizuresTMStDCS
spellingShingle Irene Gonsalvez
Primavera Spagnolo
Barbara Dworetzky
Gaston Baslet
Neurostimulation for the treatment of functional neurological disorder: A systematic review
Epilepsy & Behavior Reports
FND
Functional seizures
TMS
tDCS
title Neurostimulation for the treatment of functional neurological disorder: A systematic review
title_full Neurostimulation for the treatment of functional neurological disorder: A systematic review
title_fullStr Neurostimulation for the treatment of functional neurological disorder: A systematic review
title_full_unstemmed Neurostimulation for the treatment of functional neurological disorder: A systematic review
title_short Neurostimulation for the treatment of functional neurological disorder: A systematic review
title_sort neurostimulation for the treatment of functional neurological disorder a systematic review
topic FND
Functional seizures
TMS
tDCS
url http://www.sciencedirect.com/science/article/pii/S2589986421000757
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AT gastonbaslet neurostimulationforthetreatmentoffunctionalneurologicaldisorderasystematicreview