Somatosensory Integration and Masking of Complex Tactile Information: Peripheral and Cortical Contributions
Nerve paresthesia is a sensory impairment experienced in clinical conditions such as diabetes. Paresthesia may “mask” or “compete” with meaningful tactile information in the patient’s sensory environment. The two objectives of the present study were: (1) to determine if radiating paresthesia produce...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-12-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/10/12/954 |
| _version_ | 1797545332924481536 |
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| author | Steven R. Passmore Niyousha Mortaza Cheryl M. Glazebrook Bernadette Murphy Timothy D. Lee |
| author_facet | Steven R. Passmore Niyousha Mortaza Cheryl M. Glazebrook Bernadette Murphy Timothy D. Lee |
| author_sort | Steven R. Passmore |
| collection | DOAJ |
| description | Nerve paresthesia is a sensory impairment experienced in clinical conditions such as diabetes. Paresthesia may “mask” or “compete” with meaningful tactile information in the patient’s sensory environment. The two objectives of the present study were: (1) to determine if radiating paresthesia produces a peripheral mask, a central mask, or a combination; (2) to determine if a response competition experimental design reveals changes in somatosensory integration similar to a masking design. Experiment 1 assessed the degree of masking caused by induced radiating ulnar nerve paresthesia (a concurrent non-target stimulus) on a vibrotactile Morse code letter acquisition task using both behavioral and neurophysiological measures. Experiment 2 used a response competition design by moving the radiating paresthesia to the median nerve. This move shifted the concurrent non-target stimulus to a location spatially removed from the target stimuli. The task, behavioral and neurophysiological measures remained consistent. The induced paresthesia impacted letter acquisition differentially depending on the relative location of meaningful and non-meaningful stimulation. Paresthesia acted as a peripheral mask when presented to overlapping anatomical stimulation areas, and a central mask when presented at separate anatomical areas. These findings are discussed as they relate to masking, subcortical, and centripetal gating. |
| first_indexed | 2024-03-10T14:13:55Z |
| format | Article |
| id | doaj.art-b5fc6e0ab1d54a93a396b31477498b55 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T14:13:55Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-b5fc6e0ab1d54a93a396b31477498b552023-11-20T23:58:52ZengMDPI AGBrain Sciences2076-34252020-12-01101295410.3390/brainsci10120954Somatosensory Integration and Masking of Complex Tactile Information: Peripheral and Cortical ContributionsSteven R. Passmore0Niyousha Mortaza1Cheryl M. Glazebrook2Bernadette Murphy3Timothy D. Lee4Department of Kinesiology, McMaster University, Hamilton, ON L8S 4K1, CanadaFaculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, MB R3T 2N2, CanadaFaculty of Kinesiology and Recreation Management, University of Manitoba, Winnipeg, MB R3T 2N2, CanadaFaculty of Health Sciences, Ontario Tech University, Oshawa, ON L1G 0C5, CanadaDepartment of Kinesiology, McMaster University, Hamilton, ON L8S 4K1, CanadaNerve paresthesia is a sensory impairment experienced in clinical conditions such as diabetes. Paresthesia may “mask” or “compete” with meaningful tactile information in the patient’s sensory environment. The two objectives of the present study were: (1) to determine if radiating paresthesia produces a peripheral mask, a central mask, or a combination; (2) to determine if a response competition experimental design reveals changes in somatosensory integration similar to a masking design. Experiment 1 assessed the degree of masking caused by induced radiating ulnar nerve paresthesia (a concurrent non-target stimulus) on a vibrotactile Morse code letter acquisition task using both behavioral and neurophysiological measures. Experiment 2 used a response competition design by moving the radiating paresthesia to the median nerve. This move shifted the concurrent non-target stimulus to a location spatially removed from the target stimuli. The task, behavioral and neurophysiological measures remained consistent. The induced paresthesia impacted letter acquisition differentially depending on the relative location of meaningful and non-meaningful stimulation. Paresthesia acted as a peripheral mask when presented to overlapping anatomical stimulation areas, and a central mask when presented at separate anatomical areas. These findings are discussed as they relate to masking, subcortical, and centripetal gating.https://www.mdpi.com/2076-3425/10/12/954maskingresponse competitionMorse codeparesthesiatactile learningvibrotactile stimulus |
| spellingShingle | Steven R. Passmore Niyousha Mortaza Cheryl M. Glazebrook Bernadette Murphy Timothy D. Lee Somatosensory Integration and Masking of Complex Tactile Information: Peripheral and Cortical Contributions Brain Sciences masking response competition Morse code paresthesia tactile learning vibrotactile stimulus |
| title | Somatosensory Integration and Masking of Complex Tactile Information: Peripheral and Cortical Contributions |
| title_full | Somatosensory Integration and Masking of Complex Tactile Information: Peripheral and Cortical Contributions |
| title_fullStr | Somatosensory Integration and Masking of Complex Tactile Information: Peripheral and Cortical Contributions |
| title_full_unstemmed | Somatosensory Integration and Masking of Complex Tactile Information: Peripheral and Cortical Contributions |
| title_short | Somatosensory Integration and Masking of Complex Tactile Information: Peripheral and Cortical Contributions |
| title_sort | somatosensory integration and masking of complex tactile information peripheral and cortical contributions |
| topic | masking response competition Morse code paresthesia tactile learning vibrotactile stimulus |
| url | https://www.mdpi.com/2076-3425/10/12/954 |
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