A Comparative Study of Clinical Profile, Metabolic Parameters and Outcome of Patient Among Subtypes of Alcohol Dependence Syndrome in Tertiary Level Hospital of Kathmandu Valley
Introduction: Alcohol is a legally allowed substance used for recreation associated with harmful health consequences both on using it and trying to quit (withdrawal phase). Many patients of alcohol dependence are brought to hospital or emergency in the withdrawal phase and require intensive treatmen...
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| Format: | Article |
| Language: | English |
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HEAD Nepal
2019-06-01
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| Series: | Nepalese Medical Journal |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/nmj/article/view/24104 |
| _version_ | 1818502628713168896 |
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| author | Prabhakar Pokhrel Neena Rai Rajan Pathak Aajma Thapa Nishchal Regmi Pushpa Prasad Sharma |
| author_facet | Prabhakar Pokhrel Neena Rai Rajan Pathak Aajma Thapa Nishchal Regmi Pushpa Prasad Sharma |
| author_sort | Prabhakar Pokhrel |
| collection | DOAJ |
| description | Introduction: Alcohol is a legally allowed substance used for recreation associated with harmful health consequences both on using it and trying to quit (withdrawal phase). Many patients of alcohol dependence are brought to hospital or emergency in the withdrawal phase and require intensive treatment. It’s associated with life threatening conditions and associated with occurrences of seizures and confusion. Based on severity, it can be subtyped and managed differently. The study tries to compare and contrast the subtypes of withdrawal phases of alcohol in terms of clinical, outcome and metabolic parameters
Materials and Methods: This is a cross-sectional study of all patients diagnosed as alcohol dependence syndrome admitted over a period of two years (June 2016 to June 2018) in the psychiatric ward of KIST medical college and teaching hospital. It’s divided into two phases namely complicated and uncomplicated phase and clinical, outcome and metabolic parameters are compared and contrasted.
Results: Out of 166 patients studied, 54% of the patients were diagnosed with complicated withdrawal features. Significant changes were noticed in increase duration of stay, low level of platelets and potassium and SGPT levels in a complicated group compare to the uncomplicated group. Mortality was not seen in any of the group
Conclusions: Patients can be treated in-ward setting successfully and if the diagnosis is of complicated withdrawal then metabolic parameters like potassium, platelet level has to be taken into consideration. Complicated withdrawal features increase the chance of morbidity and increase the duration of stay. |
| first_indexed | 2024-12-10T21:12:47Z |
| format | Article |
| id | doaj.art-b5fde1f3a0344628aae1287be65c6124 |
| institution | Directory Open Access Journal |
| issn | 2631-2093 2645-8586 |
| language | English |
| last_indexed | 2024-12-10T21:12:47Z |
| publishDate | 2019-06-01 |
| publisher | HEAD Nepal |
| record_format | Article |
| series | Nepalese Medical Journal |
| spelling | doaj.art-b5fde1f3a0344628aae1287be65c61242022-12-22T01:33:24ZengHEAD NepalNepalese Medical Journal2631-20932645-85862019-06-012114514810.3126/nmj.v2i1.2410424104A Comparative Study of Clinical Profile, Metabolic Parameters and Outcome of Patient Among Subtypes of Alcohol Dependence Syndrome in Tertiary Level Hospital of Kathmandu ValleyPrabhakar Pokhrel0Neena Rai1Rajan Pathak2Aajma Thapa3Nishchal Regmi4Pushpa Prasad Sharma5KIST Medical College Teaching Hospital, Lalitpur, NepalKIST Medical College Teaching Hospital, Lalitpur, NepalKIST Medical College Teaching Hospital, Lalitpur, NepalKIST Medical College Teaching Hospital, Lalitpur, NepalKIST Medical College Teaching Hospital, Lalitpur, NepalKIST Medical College Teaching Hospital, Lalitpur, NepalIntroduction: Alcohol is a legally allowed substance used for recreation associated with harmful health consequences both on using it and trying to quit (withdrawal phase). Many patients of alcohol dependence are brought to hospital or emergency in the withdrawal phase and require intensive treatment. It’s associated with life threatening conditions and associated with occurrences of seizures and confusion. Based on severity, it can be subtyped and managed differently. The study tries to compare and contrast the subtypes of withdrawal phases of alcohol in terms of clinical, outcome and metabolic parameters Materials and Methods: This is a cross-sectional study of all patients diagnosed as alcohol dependence syndrome admitted over a period of two years (June 2016 to June 2018) in the psychiatric ward of KIST medical college and teaching hospital. It’s divided into two phases namely complicated and uncomplicated phase and clinical, outcome and metabolic parameters are compared and contrasted. Results: Out of 166 patients studied, 54% of the patients were diagnosed with complicated withdrawal features. Significant changes were noticed in increase duration of stay, low level of platelets and potassium and SGPT levels in a complicated group compare to the uncomplicated group. Mortality was not seen in any of the group Conclusions: Patients can be treated in-ward setting successfully and if the diagnosis is of complicated withdrawal then metabolic parameters like potassium, platelet level has to be taken into consideration. Complicated withdrawal features increase the chance of morbidity and increase the duration of stay.https://www.nepjol.info/index.php/nmj/article/view/24104AlcoholAlcohol dependenceAlcohol withdrawalDelerium Tremens |
| spellingShingle | Prabhakar Pokhrel Neena Rai Rajan Pathak Aajma Thapa Nishchal Regmi Pushpa Prasad Sharma A Comparative Study of Clinical Profile, Metabolic Parameters and Outcome of Patient Among Subtypes of Alcohol Dependence Syndrome in Tertiary Level Hospital of Kathmandu Valley Nepalese Medical Journal Alcohol Alcohol dependence Alcohol withdrawal Delerium Tremens |
| title | A Comparative Study of Clinical Profile, Metabolic Parameters and Outcome of Patient Among Subtypes of Alcohol Dependence Syndrome in Tertiary Level Hospital of Kathmandu Valley |
| title_full | A Comparative Study of Clinical Profile, Metabolic Parameters and Outcome of Patient Among Subtypes of Alcohol Dependence Syndrome in Tertiary Level Hospital of Kathmandu Valley |
| title_fullStr | A Comparative Study of Clinical Profile, Metabolic Parameters and Outcome of Patient Among Subtypes of Alcohol Dependence Syndrome in Tertiary Level Hospital of Kathmandu Valley |
| title_full_unstemmed | A Comparative Study of Clinical Profile, Metabolic Parameters and Outcome of Patient Among Subtypes of Alcohol Dependence Syndrome in Tertiary Level Hospital of Kathmandu Valley |
| title_short | A Comparative Study of Clinical Profile, Metabolic Parameters and Outcome of Patient Among Subtypes of Alcohol Dependence Syndrome in Tertiary Level Hospital of Kathmandu Valley |
| title_sort | comparative study of clinical profile metabolic parameters and outcome of patient among subtypes of alcohol dependence syndrome in tertiary level hospital of kathmandu valley |
| topic | Alcohol Alcohol dependence Alcohol withdrawal Delerium Tremens |
| url | https://www.nepjol.info/index.php/nmj/article/view/24104 |
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