miR-1205/DNAJB1 reverses docetaxel chemoresistance in human triple negative breast carcinoma cells via regulation of mutp53/TAp63 signaling

miR-1205/DNAJB1 reverses docetaxel chemoresistance in human triple negative breast carcinoma cells via regulation of mutp53/TAp63 signaling

Chemoresistance is the major cause of therapeutic failure in human triple negative breast carcinoma (TNBC). Docetaxel (DOC), a first-line therapeutic drug in TNBC treatment, is limited for long-term use due to the development of chemoresistance. Thus, overcoming chemoresistance of DOC remains an imp...

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Bibliographic Details
Main Authors: Yin Yongxiang, Zhang Jinqiu, Ma Tao, Chen Daozhen, Lu Daru
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2021-12-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
triple negative breast carcinoma
docetaxel resistance
miR-1205/DNAJB1
mutp53/TAp63 signaling
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2021006

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