Epigenetic characterization of CDKN1C in placenta samples from non-syndromic intrauterine growth restriction
The Cyclin-dependent kinase (CDK)-inhibitor 1C (CDKN1C) gene is expressed from the maternal allele and is located within the centromeric imprinted domain at chromosome 11p15. It is a negative regulator of proliferation, with loss-of-function mutations associated with the overgrowth disorder Beckwith...
Main Authors: | David eMonk, Miriam eLópez-Abad, Isabel eIglesias-Platas |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-04-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00062/full |
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