Tubular HIPK2 is a key contributor to renal fibrosis

Tubular HIPK2 is a key contributor to renal fibrosis

We previously used global Hipk2-null mice in various models of kidney disease to demonstrate the central role of homeodomain-interacting protein kinase 2 (HIPK2) in renal fibrosis development. However, renal tubular epithelial cell–specific (RTEC-specific) HIPK2 function in renal fibrogenesis has ye...

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Bibliographic Details
Main Authors:	Wenzhen Xiao, Jing E, Li Bao, Ying Fan, Yuanmeng Jin, Andrew Wang, David Bauman, Zhengzhe Li, Ya-Li Zheng, Ruijie Liu, Kyung Lee, John Cijiang He
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2020-09-01
Series:	JCI Insight
Subjects:	Nephrology
Online Access:	https://doi.org/10.1172/jci.insight.136004

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