Condition of pro-oxidant system in guinea pigs’ bronchi in experimental allergic alveolitis development and their correction with thiotriazolin
Exogenic allergic alveolitis has been ascribed to multiple inhaled antigens found in a large variety of environmental settings. The immune mechanisms leading to this deases development are still incompletely understood. Initially, believed to be a classes III and IV immune response, we now have a c...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2017-06-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/24267 |
| _version_ | 1818049135643721728 |
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| author | Mariana Ljubomurivna Baida Mariana Muchailivna Fyrduchko-Regeda Natalia Grugorivna Sementsiv |
| author_facet | Mariana Ljubomurivna Baida Mariana Muchailivna Fyrduchko-Regeda Natalia Grugorivna Sementsiv |
| author_sort | Mariana Ljubomurivna Baida |
| collection | DOAJ |
| description |
Exogenic allergic alveolitis has been ascribed to multiple inhaled antigens found in a large variety of environmental settings. The immune mechanisms leading to this deases development are still incompletely understood. Initially, believed to be a classes III and IV immune response, we now have a clearer understanding of the complex inflammatory events involved. These include the release of pro inflammatory cytokines and a decrease in the immune control mechanisms via surfactant, dendritic and T-regulatory cells. Free radicals and reactive oxygen species could play a major role in the pathophysiology of allergic alveolitis . Despite the improved understanding, the treatment and outcome of this pathology have not known enough. This work determinate on accumulation of lipid peroxidaton products in the animals` bronchi during experimental allergic alveolitis and corrective effect of antioxidant-thiotriazolin on these indicators.
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| first_indexed | 2024-12-10T10:32:46Z |
| format | Article |
| id | doaj.art-b6121dfee3be45ecb91a1c38362d4d05 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-10T10:32:46Z |
| publishDate | 2017-06-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-b6121dfee3be45ecb91a1c38362d4d052022-12-22T01:52:32ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-06-0176Condition of pro-oxidant system in guinea pigs’ bronchi in experimental allergic alveolitis development and their correction with thiotriazolinMariana Ljubomurivna Baida0Mariana Muchailivna Fyrduchko-Regeda1Natalia Grugorivna Sementsiv2Danylo Halytsky Lviv National Medical UniversityDanylo Halytsky Lviv National Medical UniversityDanylo Halytsky Lviv National Medical University Exogenic allergic alveolitis has been ascribed to multiple inhaled antigens found in a large variety of environmental settings. The immune mechanisms leading to this deases development are still incompletely understood. Initially, believed to be a classes III and IV immune response, we now have a clearer understanding of the complex inflammatory events involved. These include the release of pro inflammatory cytokines and a decrease in the immune control mechanisms via surfactant, dendritic and T-regulatory cells. Free radicals and reactive oxygen species could play a major role in the pathophysiology of allergic alveolitis . Despite the improved understanding, the treatment and outcome of this pathology have not known enough. This work determinate on accumulation of lipid peroxidaton products in the animals` bronchi during experimental allergic alveolitis and corrective effect of antioxidant-thiotriazolin on these indicators. https://apcz.umk.pl/JEHS/article/view/24267experimental allergic alveolitismalonic dialdegydeconjugated diensthiotriazolin |
| spellingShingle | Mariana Ljubomurivna Baida Mariana Muchailivna Fyrduchko-Regeda Natalia Grugorivna Sementsiv Condition of pro-oxidant system in guinea pigs’ bronchi in experimental allergic alveolitis development and their correction with thiotriazolin Journal of Education, Health and Sport experimental allergic alveolitis malonic dialdegyde conjugated diens thiotriazolin |
| title | Condition of pro-oxidant system in guinea pigs’ bronchi in experimental allergic alveolitis development and their correction with thiotriazolin |
| title_full | Condition of pro-oxidant system in guinea pigs’ bronchi in experimental allergic alveolitis development and their correction with thiotriazolin |
| title_fullStr | Condition of pro-oxidant system in guinea pigs’ bronchi in experimental allergic alveolitis development and their correction with thiotriazolin |
| title_full_unstemmed | Condition of pro-oxidant system in guinea pigs’ bronchi in experimental allergic alveolitis development and their correction with thiotriazolin |
| title_short | Condition of pro-oxidant system in guinea pigs’ bronchi in experimental allergic alveolitis development and their correction with thiotriazolin |
| title_sort | condition of pro oxidant system in guinea pigs bronchi in experimental allergic alveolitis development and their correction with thiotriazolin |
| topic | experimental allergic alveolitis malonic dialdegyde conjugated diens thiotriazolin |
| url | https://apcz.umk.pl/JEHS/article/view/24267 |
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