In utero and post-natal opioid exposure followed by mild traumatic brain injury contributes to cortical neuroinflammation, mitochondrial dysfunction, and behavioral deficits in juvenile rats

In utero and post-natal opioid exposure followed by mild traumatic brain injury contributes to cortical neuroinflammation, mitochondrial dysfunction, and behavioral deficits in juvenile rats

Maternal opioid use poses a significant health concern not just to the expectant mother but also to the fetus. Notably, increasing numbers of children born suffering from neonatal opioid withdrawal syndrome (NOWS) further compounds the crisis. While epidemiological research has shown the heightened...

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Bibliographic Details
Main Authors: Austin M. Gowen, Jina Yi, Kelly Stauch, Luke Miles, Sanjay Srinivasan, Katherine Odegaard, Gurudutt Pendyala, Sowmya V. Yelamanchili
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Opioid
Neonatal opioid withdrawal syndrome
Minor traumatic brain injury
Cortex
Synaptosome
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354623000832

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