Investigating the <i>Leishmania donovani sacp</i> Gene and Its Role in Macrophage Infection and Survival in Mice

Investigating the <i>Leishmania donovani sacp</i> Gene and Its Role in Macrophage Infection and Survival in Mice

The protozoan parasite <i>Leishmania donovani</i> is a causative agent of the neglected tropical disease known as visceral leishmaniasis, which can be lethal when untreated. Studying <i>Leishmania</i> viru-lence factors is crucial in determining how the parasite causes diseas...

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Bibliographic Details
Main Authors: Kayla Paulini, Patrick Lypaczewski, Wen-Wei Zhang, Dilhan J. Perera, Momar Ndao, Greg Matlashewski
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Tropical Medicine and Infectious Disease
Subjects:
visceral leishmaniasis
CRISPR-Cas9
whole-genome sequencing
virulence
drug target
Online Access:https://www.mdpi.com/2414-6366/7/11/384

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