HOMER3 promotes non-small cell lung cancer growth and metastasis primarily through GABPB1-mediated mitochondrial metabolism

Abstract Cancer metabolism has emerged as a major target for cancer therapy, while the state of mitochondrial drugs has remained largely unexplored, partly due to an inadequate understanding of various mitochondrial functions in tumor contexts. Here, we report that HOMER3 is highly expressed in non-...

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Bibliographic Details
Main Authors: Teng Sun, Chao Song, Guoqing Zhao, Shoujie Feng, Jianhao Wei, Lixia Zhang, Xiangming Liu, Zhuoqun Li, Hao Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06335-5