Efficacy of Oral Encochleated Amphotericin B in a Mouse Model of Cryptococcal Meningoencephalitis
ABSTRACT Cryptococcus neoformans is an encapsulated yeast responsible for approximately a quarter of a million deaths worldwide annually despite therapy, and upwards of 11% of HIV/AIDS-related deaths, rivaling the impact of tuberculosis and malaria. However, the most effective antifungal agent, amph...
Main Authors: | R. Lu, C. Hollingsworth, J. Qiu, A. Wang, E. Hughes, X. Xin, K. M. Konrath, W. Elsegeiny, Yoon-Dong Park, L. Atakulu, J. C. Craft, E. C. Tramont, R. Mannino, P. R. Williamson |
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Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2019-06-01
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Series: | mBio |
Subjects: | |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.00724-19 |
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