Higher-order thalamic nuclei facilitate the generalization and maintenance of spike-and-wave discharges of absence seizures

Higher-order thalamic nuclei facilitate the generalization and maintenance of spike-and-wave discharges of absence seizures

Spike-and-wave discharges (SWDs), generated by the cortico-thalamo-cortical (CTC) network, are pathological, large amplitude oscillations and the hallmark of absence seizures (ASs). SWDs begin in a cortical initiation network in both humans and animal models, including the Genetic Absence Epilepsy R...

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Bibliographic Details
Main Authors: Zoe Atherton, Olivér Nagy, Lívia Barcsai, Péter Sere, Nikolett Zsigri, Tamás Földi, Levente Gellért, Antal Berényi, Vincenzo Crunelli, Magor L. Lőrincz
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Neurobiology of Disease
Subjects:
Epilepsy
Somatosensory cortex
Thalamus
Higher-order thalamic nuclei
Ensemble recordings
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123000396

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