Numerical modelling of the V-J combinations of the T cell receptor TRA/TRD locus.

Numerical modelling of the V-J combinations of the T cell receptor TRA/TRD locus.

T-Cell antigen Receptor (TR) repertoire is generated through rearrangements of V and J genes encoding alpha and beta chains. The quantification and frequency for every V-J combination during ontogeny and development of the immune system remain to be precisely established. We have addressed this issu...

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Bibliographic Details
Main Authors: Florence Thuderoz, Maria-Ana Simonet, Olivier Hansen, Nicolas Pasqual, Aurélie Dariz, Thierry Pascal Baum, Vivien Hierle, Jacques Demongeot, Patrice Noël Marche, Evelyne Jouvin-Marche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2824756?pdf=render

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