Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke?
Abstract Background Stroke can affect any portion of the central nervous system leading to a wide variety of symptoms depending on the part that is involved. Diffusion tensor imaging (DTI) is an emerging neuroimaging technique that allows measuring the integrity of white matter tracts. Objectives Th...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2020-06-01
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| Series: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s41983-020-00176-1 |
| _version_ | 1828958979201433600 |
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| author | Mervat Mostafa Maged Abdel Naseer Ramy Edward Mohammad Edrees Dalia M. Labib |
| author_facet | Mervat Mostafa Maged Abdel Naseer Ramy Edward Mohammad Edrees Dalia M. Labib |
| author_sort | Mervat Mostafa |
| collection | DOAJ |
| description | Abstract Background Stroke can affect any portion of the central nervous system leading to a wide variety of symptoms depending on the part that is involved. Diffusion tensor imaging (DTI) is an emerging neuroimaging technique that allows measuring the integrity of white matter tracts. Objectives The objective of this study is to find out if the diffusion tensor tractography technique can provide prognostic information regarding clinical outcome following ischemic stroke. Subjects and methods Forty patients with acute ischemic stroke were studied with DTI. Size of infraction, degree of reduction of fractional anisotropy (FA), and pattern of corticospinal tract (CST) affection were identified. We assessed our patients according to the National Institute of Health Stroke Scale (NIHSS) and Medical Research Council (MRC) scale at onset of stroke and 3 months later. Results FA reduction was correlated with MRC and NIHSS on admission (P < 0.001, 0.004 respectively) and after 3 months (P < 0.001, 0.013 respectively). The pattern of CST affection was associated with NIHSS and MRC after 3 months (P = 0.035, 0.001 respectively). Conclusion DTI may be an indirect indicator of the ischemic stroke outcome. |
| first_indexed | 2024-12-14T08:59:02Z |
| format | Article |
| id | doaj.art-b62c11ebd0e74f10b36357a1df582e03 |
| institution | Directory Open Access Journal |
| issn | 1687-8329 |
| language | English |
| last_indexed | 2024-12-14T08:59:02Z |
| publishDate | 2020-06-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| spelling | doaj.art-b62c11ebd0e74f10b36357a1df582e032022-12-21T23:08:52ZengSpringerOpenThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery1687-83292020-06-015611810.1186/s41983-020-00176-1Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke?Mervat Mostafa0Maged Abdel Naseer1Ramy Edward2Mohammad Edrees3Dalia M. Labib4Department of Neurology, Cairo UniversityDepartment of Neurology, Cairo UniversityDepartment of Radio-diagnosis, Cairo UniversityDepartment of Neurology, Cairo UniversityDepartment of Neurology, Cairo UniversityAbstract Background Stroke can affect any portion of the central nervous system leading to a wide variety of symptoms depending on the part that is involved. Diffusion tensor imaging (DTI) is an emerging neuroimaging technique that allows measuring the integrity of white matter tracts. Objectives The objective of this study is to find out if the diffusion tensor tractography technique can provide prognostic information regarding clinical outcome following ischemic stroke. Subjects and methods Forty patients with acute ischemic stroke were studied with DTI. Size of infraction, degree of reduction of fractional anisotropy (FA), and pattern of corticospinal tract (CST) affection were identified. We assessed our patients according to the National Institute of Health Stroke Scale (NIHSS) and Medical Research Council (MRC) scale at onset of stroke and 3 months later. Results FA reduction was correlated with MRC and NIHSS on admission (P < 0.001, 0.004 respectively) and after 3 months (P < 0.001, 0.013 respectively). The pattern of CST affection was associated with NIHSS and MRC after 3 months (P = 0.035, 0.001 respectively). Conclusion DTI may be an indirect indicator of the ischemic stroke outcome.http://link.springer.com/article/10.1186/s41983-020-00176-1Diffusion tensor imagingTractographyStrokePrognosisMRCNIHSS |
| spellingShingle | Mervat Mostafa Maged Abdel Naseer Ramy Edward Mohammad Edrees Dalia M. Labib Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke? The Egyptian Journal of Neurology, Psychiatry and Neurosurgery Diffusion tensor imaging Tractography Stroke Prognosis MRC NIHSS |
| title | Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke? |
| title_full | Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke? |
| title_fullStr | Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke? |
| title_full_unstemmed | Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke? |
| title_short | Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke? |
| title_sort | can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke |
| topic | Diffusion tensor imaging Tractography Stroke Prognosis MRC NIHSS |
| url | http://link.springer.com/article/10.1186/s41983-020-00176-1 |
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