Plant Defensins from a Structural Perspective
Plant defensins form a family of proteins with a broad spectrum of protective activities against fungi, bacteria, and insects. Furthermore, some plant defensins have revealed anticancer activity. In general, plant defensins are non-toxic to plant and mammalian cells, and interest in using them for b...
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Format: | Article |
Language: | English |
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MDPI AG
2020-07-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/21/15/5307 |
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author | Valentina Kovaleva Irina Bukhteeva Oleg Y. Kit Irina V. Nesmelova |
author_facet | Valentina Kovaleva Irina Bukhteeva Oleg Y. Kit Irina V. Nesmelova |
author_sort | Valentina Kovaleva |
collection | DOAJ |
description | Plant defensins form a family of proteins with a broad spectrum of protective activities against fungi, bacteria, and insects. Furthermore, some plant defensins have revealed anticancer activity. In general, plant defensins are non-toxic to plant and mammalian cells, and interest in using them for biotechnological and medicinal purposes is growing. Recent studies provided significant insights into the mechanisms of action of plant defensins. In this review, we focus on structural and dynamics aspects and discuss structure-dynamics-function relations of plant defensins. |
first_indexed | 2024-03-10T18:12:20Z |
format | Article |
id | doaj.art-b62dccc4180245ed8f9763837529c5eb |
institution | Directory Open Access Journal |
issn | 1661-6596 1422-0067 |
language | English |
last_indexed | 2024-03-10T18:12:20Z |
publishDate | 2020-07-01 |
publisher | MDPI AG |
record_format | Article |
series | International Journal of Molecular Sciences |
spelling | doaj.art-b62dccc4180245ed8f9763837529c5eb2023-11-20T08:01:27ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-07-012115530710.3390/ijms21155307Plant Defensins from a Structural PerspectiveValentina Kovaleva0Irina Bukhteeva1Oleg Y. Kit2Irina V. Nesmelova3Laboratory of Molecular Genetic Markers in Plants, Ukrainian National Forestry University, 79057 Lviv, UkraineDepartment of Physics and Optical Sciences and Center for Biomedical Engineering and Science, University of North Carolina at Charlotte, Charlotte, NC 28223, USAInterregional Academy of Personal Management, 79059 Lviv, UkraineDepartment of Physics and Optical Sciences and Center for Biomedical Engineering and Science, University of North Carolina at Charlotte, Charlotte, NC 28223, USAPlant defensins form a family of proteins with a broad spectrum of protective activities against fungi, bacteria, and insects. Furthermore, some plant defensins have revealed anticancer activity. In general, plant defensins are non-toxic to plant and mammalian cells, and interest in using them for biotechnological and medicinal purposes is growing. Recent studies provided significant insights into the mechanisms of action of plant defensins. In this review, we focus on structural and dynamics aspects and discuss structure-dynamics-function relations of plant defensins.https://www.mdpi.com/1422-0067/21/15/5307plant defensinstructuredynamicsγ-coreNMRx-ray |
spellingShingle | Valentina Kovaleva Irina Bukhteeva Oleg Y. Kit Irina V. Nesmelova Plant Defensins from a Structural Perspective International Journal of Molecular Sciences plant defensin structure dynamics γ-core NMR x-ray |
title | Plant Defensins from a Structural Perspective |
title_full | Plant Defensins from a Structural Perspective |
title_fullStr | Plant Defensins from a Structural Perspective |
title_full_unstemmed | Plant Defensins from a Structural Perspective |
title_short | Plant Defensins from a Structural Perspective |
title_sort | plant defensins from a structural perspective |
topic | plant defensin structure dynamics γ-core NMR x-ray |
url | https://www.mdpi.com/1422-0067/21/15/5307 |
work_keys_str_mv | AT valentinakovaleva plantdefensinsfromastructuralperspective AT irinabukhteeva plantdefensinsfromastructuralperspective AT olegykit plantdefensinsfromastructuralperspective AT irinavnesmelova plantdefensinsfromastructuralperspective |