Physical activity and risks of esophageal and gastric cancers: a meta-analysis.
BACKGROUND: The incidence of esophageal and gastric cancer has been increasing rapidly worldwide in recent years, although the reason for this increase is unclear. Here, a statistical synthesis of studies that evaluated the association between physical activity, a well-known protecting factor agains...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3916353?pdf=render |
| _version_ | 1811228622822834176 |
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| author | Yi Chen Chaohui Yu Youming Li |
| author_facet | Yi Chen Chaohui Yu Youming Li |
| author_sort | Yi Chen |
| collection | DOAJ |
| description | BACKGROUND: The incidence of esophageal and gastric cancer has been increasing rapidly worldwide in recent years, although the reason for this increase is unclear. Here, a statistical synthesis of studies that evaluated the association between physical activity, a well-known protecting factor against death and other chronic diseases, and the risk of esophageal and gastric cancer was performed. METHODS: Potentially suitable studies were identified using Medline and Embase. The reference lists of all included articles and those of several recent reviews were searched manually. Studies were included if they (1) were published as case-control or cohort studies evaluating the association between physical activity and risk of esophageal or gastric cancer; and (2) reported point estimates (i.e., risk ratios, odds ratios) and measures of variability (i.e., 95% confidence intervals [CIs]) for physical activity and risk of esophageal or gastric cancer. RESULTS: Fifteen studies were identified (7 cohorts, 8 case-controls; 984 esophageal and 7,087 gastric cancers). Collectively, they indicated that the risk of gastric cancer was 13% lower among the most physically active people than among the least active people (RR = 0.87, 95% confidence interval [CI] = 0.78 to 0.97) and that of esophageal cancer was 27% lower (RR = 0.73, 95% CI = 0.56 to 0.97). CONCLUSIONS: Pooled results from observational studies support a protective effect of physical activity against both esophageal and gastric cancer. |
| first_indexed | 2024-04-12T10:01:09Z |
| format | Article |
| id | doaj.art-b634c83e6f584f7b977e2e2ae8eb4229 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T10:01:09Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-b634c83e6f584f7b977e2e2ae8eb42292022-12-22T03:37:34ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0192e8808210.1371/journal.pone.0088082Physical activity and risks of esophageal and gastric cancers: a meta-analysis.Yi ChenChaohui YuYouming LiBACKGROUND: The incidence of esophageal and gastric cancer has been increasing rapidly worldwide in recent years, although the reason for this increase is unclear. Here, a statistical synthesis of studies that evaluated the association between physical activity, a well-known protecting factor against death and other chronic diseases, and the risk of esophageal and gastric cancer was performed. METHODS: Potentially suitable studies were identified using Medline and Embase. The reference lists of all included articles and those of several recent reviews were searched manually. Studies were included if they (1) were published as case-control or cohort studies evaluating the association between physical activity and risk of esophageal or gastric cancer; and (2) reported point estimates (i.e., risk ratios, odds ratios) and measures of variability (i.e., 95% confidence intervals [CIs]) for physical activity and risk of esophageal or gastric cancer. RESULTS: Fifteen studies were identified (7 cohorts, 8 case-controls; 984 esophageal and 7,087 gastric cancers). Collectively, they indicated that the risk of gastric cancer was 13% lower among the most physically active people than among the least active people (RR = 0.87, 95% confidence interval [CI] = 0.78 to 0.97) and that of esophageal cancer was 27% lower (RR = 0.73, 95% CI = 0.56 to 0.97). CONCLUSIONS: Pooled results from observational studies support a protective effect of physical activity against both esophageal and gastric cancer.http://europepmc.org/articles/PMC3916353?pdf=render |
| spellingShingle | Yi Chen Chaohui Yu Youming Li Physical activity and risks of esophageal and gastric cancers: a meta-analysis. PLoS ONE |
| title | Physical activity and risks of esophageal and gastric cancers: a meta-analysis. |
| title_full | Physical activity and risks of esophageal and gastric cancers: a meta-analysis. |
| title_fullStr | Physical activity and risks of esophageal and gastric cancers: a meta-analysis. |
| title_full_unstemmed | Physical activity and risks of esophageal and gastric cancers: a meta-analysis. |
| title_short | Physical activity and risks of esophageal and gastric cancers: a meta-analysis. |
| title_sort | physical activity and risks of esophageal and gastric cancers a meta analysis |
| url | http://europepmc.org/articles/PMC3916353?pdf=render |
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