In Vitro Metabolic Transformation of Pharmaceuticals by Hepatic S9 Fractions from Common Carp <i>(Cyprinus carpio)</i>

In Vitro Metabolic Transformation of Pharmaceuticals by Hepatic S9 Fractions from Common Carp <i>(Cyprinus carpio)</i>

Water from wastewater treatment plants contains concentrations of pharmaceutically active compounds as high as micrograms per liter, which can adversely affect fish health and behavior, and contaminate the food chain. Here, we tested the ability of the common carp hepatic S9 fraction to produce the...

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Bibliographic Details
Main Authors: Viktoriia Burkina, Sidika Sakalli, Pham Thai Giang, Kateřina Grabicová, Andrea Vojs Staňová, Galia Zamaratskaia, Vladimir Zlabek
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Molecules
Subjects:
cytochrome P450
metabolite formation
citalopram
sertraline
venlafaxine
metoprolol
Online Access:https://www.mdpi.com/1420-3049/25/11/2690

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