Improvement of Microbial Cell Concentration Technology in the Production of Live Plague Vaccine in the Form of Orodispersible Tablets

Improvement of Microbial Cell Concentration Technology in the Production of Live Plague Vaccine in the Form of Orodispersible Tablets

The aim of the study was to improve the procedure for the Yersinia pestis EV strain cell concentration using the system for tangential flow microfiltration with the ASF-020 filter support unit.Materials and methods. The study used the vaccine Y. pestis EV strain derived from NIIEG cell line. Submerg...

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Bibliographic Details
Main Authors:	D. A. Sharov, A. A. Leshchenko, S. V. Bagin, S. V. Logvinov, D. A. Mokhov, A. V. Ezhov, A. G. Lazykin, V. V. Krupin, I. V. Kosenkov
Format:	Article
Language:	Russian
Published:	Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe” 2021-02-01
Series:	Проблемы особо опасных инфекций
Subjects:	yersinia pestis ev vaccine strain live plague vaccine live plague vaccine manufacturing technology microbial suspension concentration mass balance and microfiltration
Online Access:	https://journal.microbe.ru/jour/article/view/1417

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