The cytoplasmic N-terminal tail of Zika virus NS4A protein forms oligomers in the absence of detergent or lipids
Abstract The non-structural (NS) NS4A protein in flaviviruses has three predicted transmembrane domains, is critical for virulence and participates in membrane morphogenesis. In Dengue virus (DENV), both hydrophylic N-terminal tail and its first transmembrane domain participate in the formation of o...
Hauptverfasser: | , , |
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Format: | Artikel |
Sprache: | English |
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Nature Portfolio
2023-05-01
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Schriftenreihe: | Scientific Reports |
Online Zugang: | https://doi.org/10.1038/s41598-023-34621-x |