Secondary developmental glaucoma in eyes with congenital aphakia
Purpose: To describe the clinical spectrum and management of glaucoma in congenital aphakia. Methods: The demographics and clinical spectrum of eyes with congenital aphakia with and without glaucoma were compared, and management outcomes of congenital aphakia cases with glaucoma were studied retrosp...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=3;spage=834;epage=836;aulast=Badakere |
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| author | Swathi Vallabh Badakere Simranjeet Aulakh Divya Sree Ramya Achanta Raghava Chary Sirisha Senthil Sunita Chaurasia Muralidhar Ramappa Deepak P Edward |
| author_facet | Swathi Vallabh Badakere Simranjeet Aulakh Divya Sree Ramya Achanta Raghava Chary Sirisha Senthil Sunita Chaurasia Muralidhar Ramappa Deepak P Edward |
| author_sort | Swathi Vallabh Badakere |
| collection | DOAJ |
| description | Purpose: To describe the clinical spectrum and management of glaucoma in congenital aphakia. Methods: The demographics and clinical spectrum of eyes with congenital aphakia with and without glaucoma were compared, and management outcomes of congenital aphakia cases with glaucoma were studied retrospectively between April 2000 and June 2020. Results: There were a total of 168 eyes (84 subjects) with a diagnosis of congenital aphakia, of which 29 eyes of 18 subjects were diagnosed with glaucoma. Corneal opacity was the presenting complaint in 26/29 eyes with glaucoma and 139/139 eyes without glaucoma. The (interquartile range (IQR)) horizontal corneal diameter was 10.5mm (IQR, 9.0-12.5) and 8mm (IQR, 5-10) in eyes with and without glaucoma (P = 0.01), respectively. The median (IQR) axial length was 17.5mm (IQR, 13.5-19.5) and 15mm (IQR, 14-16) mm in eyes with and without glaucoma (P = 0.03), respectively. Nineteen eyes with glaucoma had adequate intraocular pressure (IOP) control with one medication. Three eyes underwent transscleral diode cyclophotocoagulation and maintained IOP without medications. Three eyes underwent trabeculectomy and trabeculotomy, trabeculectomy followed by penetrating keratoplasty, and trabeculectomy, respectively, of which two eyes became phthisical. At the last follow-up, the median (IQR) IOP was 14 mm Hg (IQR, 14-17) Hg. The median (IQR) follow-up duration was 4.53 months (IQR, 2.03- 48.06). Conclusion: One-fifth of the eyes with congenital aphakia had secondary developmental glaucoma. The corneal diameter and axial lengths were higher in the eyes with glaucoma compared to eyes without glaucoma. Medical management is the preferred short-term mode of IOP control. Transscleral cyclophotocoagulation may be preferred over surgical intervention. |
| first_indexed | 2024-12-19T21:41:23Z |
| format | Article |
| id | doaj.art-b63aa6c7c42d4dd5beca0c0b4c378b8a |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-19T21:41:23Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-b63aa6c7c42d4dd5beca0c0b4c378b8a2022-12-21T20:04:39ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892022-01-0170383483610.4103/ijo.IJO_1782_21Secondary developmental glaucoma in eyes with congenital aphakiaSwathi Vallabh BadakereSimranjeet AulakhDivya Sree Ramya AchantaRaghava CharySirisha SenthilSunita ChaurasiaMuralidhar RamappaDeepak P EdwardPurpose: To describe the clinical spectrum and management of glaucoma in congenital aphakia. Methods: The demographics and clinical spectrum of eyes with congenital aphakia with and without glaucoma were compared, and management outcomes of congenital aphakia cases with glaucoma were studied retrospectively between April 2000 and June 2020. Results: There were a total of 168 eyes (84 subjects) with a diagnosis of congenital aphakia, of which 29 eyes of 18 subjects were diagnosed with glaucoma. Corneal opacity was the presenting complaint in 26/29 eyes with glaucoma and 139/139 eyes without glaucoma. The (interquartile range (IQR)) horizontal corneal diameter was 10.5mm (IQR, 9.0-12.5) and 8mm (IQR, 5-10) in eyes with and without glaucoma (P = 0.01), respectively. The median (IQR) axial length was 17.5mm (IQR, 13.5-19.5) and 15mm (IQR, 14-16) mm in eyes with and without glaucoma (P = 0.03), respectively. Nineteen eyes with glaucoma had adequate intraocular pressure (IOP) control with one medication. Three eyes underwent transscleral diode cyclophotocoagulation and maintained IOP without medications. Three eyes underwent trabeculectomy and trabeculotomy, trabeculectomy followed by penetrating keratoplasty, and trabeculectomy, respectively, of which two eyes became phthisical. At the last follow-up, the median (IQR) IOP was 14 mm Hg (IQR, 14-17) Hg. The median (IQR) follow-up duration was 4.53 months (IQR, 2.03- 48.06). Conclusion: One-fifth of the eyes with congenital aphakia had secondary developmental glaucoma. The corneal diameter and axial lengths were higher in the eyes with glaucoma compared to eyes without glaucoma. Medical management is the preferred short-term mode of IOP control. Transscleral cyclophotocoagulation may be preferred over surgical intervention.http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=3;spage=834;epage=836;aulast=Badakereclinical spectrum of glaucomacongenital aphakiasecondary developmental glaucoma |
| spellingShingle | Swathi Vallabh Badakere Simranjeet Aulakh Divya Sree Ramya Achanta Raghava Chary Sirisha Senthil Sunita Chaurasia Muralidhar Ramappa Deepak P Edward Secondary developmental glaucoma in eyes with congenital aphakia Indian Journal of Ophthalmology clinical spectrum of glaucoma congenital aphakia secondary developmental glaucoma |
| title | Secondary developmental glaucoma in eyes with congenital aphakia |
| title_full | Secondary developmental glaucoma in eyes with congenital aphakia |
| title_fullStr | Secondary developmental glaucoma in eyes with congenital aphakia |
| title_full_unstemmed | Secondary developmental glaucoma in eyes with congenital aphakia |
| title_short | Secondary developmental glaucoma in eyes with congenital aphakia |
| title_sort | secondary developmental glaucoma in eyes with congenital aphakia |
| topic | clinical spectrum of glaucoma congenital aphakia secondary developmental glaucoma |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2022;volume=70;issue=3;spage=834;epage=836;aulast=Badakere |
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