Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression
The melanoma-associated antigen family A (MAGEA) antigens are expressed in a wide variety of malignant tumors but not in adult somatic cells, rendering them attractive targets for cancer immunotherapy. Here we show that a number of cancer-associated MAGEA mutants that undergo proteasome-dependent de...
Main Authors: | Yiu Huen Tsang, Yumeng Wang, Kathleen Kong, Caitlin Grzeskowiak, Oksana Zagorodna, Turgut Dogruluk, Hengyu Lu, Nicole Villafane, Venkata Hemanjani Bhavana, Daniela Moreno, Sarah H Elsea, Han Liang, Gordon B Mills, Kenneth L Scott |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/48963 |
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