A methylation- and immune-related lncRNA signature to predict ovarian cancer outcome and uncover mechanisms of chemoresistance

A methylation- and immune-related lncRNA signature to predict ovarian cancer outcome and uncover mechanisms of chemoresistance

Abstract Tumor-associated lncRNAs regulated by epigenetic modification switches mediate immune escape and chemoresistance in ovarian cancer (OC). However, the underlying mechanisms and concrete targets have not been systematically elucidated. Here, we discovered that methylation modifications played...

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Bibliographic Details
Main Authors: Lu Chen, Wujiang Gao, Li Lin, Chunli Sha, Taoqiong Li, Qi Chen, Hong Wei, Meiling Yang, Jie Xing, Mengxue Zhang, Shijie Zhao, Wenlin Xu, Yuefeng Li, Lulu Long, Xiaolan Zhu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Journal of Ovarian Research
Subjects:
mrlncRNA
irlncRNA
OC
Chemoresistance
Tumor-infiltrating
Online Access:https://doi.org/10.1186/s13048-023-01260-9

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