Antiplatelet agents: an overview

Platelets play a major role in normal hemostatic and thrombotic processes. Aggregation of platelets presents the key pathophysiological step in the development of cardiovascular diseases; hence, antiplatelet agents remain crucial in the treatment of cardiovascular diseases. They may target the three...

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Bibliographic Details
Main Authors: Asma Haffouz, Ali Gargouri, Basma Hadjkacem
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of the Arab Society for Medical Research
Subjects:
Online Access:http://www.new.asmr.eg.net/article.asp?issn=1687-4293;year=2023;volume=18;issue=1;spage=13;epage=25;aulast=Haffouz
Description
Summary:Platelets play a major role in normal hemostatic and thrombotic processes. Aggregation of platelets presents the key pathophysiological step in the development of cardiovascular diseases; hence, antiplatelet agents remain crucial in the treatment of cardiovascular diseases. They may target the three principal phases leading to thrombogenesis, including platelet adhesion, activation, and aggregation. This review presents an overview of the currently available antiplatelet agents, with a particular focus on their targets, pharmacological properties, and limitation of use.
ISSN:1687-4293
2090-3286