Pain Sensitivity, Negative Affect, and Alcohol Use Disorder Status: A Moderated Mediation Study of Emotion Dysregulation
Previous work suggests that the association between pain and emotional processes among individuals with alcohol use disorder (AUD) may differ from healthy controls. This study investigates whether pain sensitivity mediates the association between negative affect and emotional dysregulation and wheth...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-03-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/6/1321 |
| _version_ | 1797540378845380608 |
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| author | Maciej Kopera Elisa M. Trucco Hubert Suszek Paweł Kobyliński Paweł Wiśniewski Marcin Wojnar Andrzej Jakubczyk |
| author_facet | Maciej Kopera Elisa M. Trucco Hubert Suszek Paweł Kobyliński Paweł Wiśniewski Marcin Wojnar Andrzej Jakubczyk |
| author_sort | Maciej Kopera |
| collection | DOAJ |
| description | Previous work suggests that the association between pain and emotional processes among individuals with alcohol use disorder (AUD) may differ from healthy controls. This study investigates whether pain sensitivity mediates the association between negative affect and emotional dysregulation and whether this association differs across AUD status using moderated mediation. The sample included 165 individuals diagnosed with AUD and 110 healthy controls. Of interest was pain sensitivity, as assessed with the Pain Sensitivity Questionnaire, negative affect, as assessed with the Beck Depression Inventory, and emotional dysregulation, as assessed with the Difficulties in Emotional regulation Scale. Age, biological sex, and current pain severity were included as covariates. The results support a moderated partial mediation model that explained 44% of the variance in emotional dysregulation. The findings indicate that negative affect is related to higher pain sensitivity across groups. Moreover, pain sensitivity partially mediated the association between negative affect and emotional dysregulation, but in opposite directions depending on AUD status. Among healthy controls, greater pain sensitivity was related to better emotional regulation, while greater pain sensitivity led to greater emotional dysregulation among individuals with AUD. The potential parallels in the underlying neurobiological mechanisms of emotionality, pain, and AUD suggest that interventions targeting pain may improve adaptive affect regulation skills, which in turn could reduce negative affect and its effect on pain sensitivity among individuals with AUD. |
| first_indexed | 2024-03-10T12:59:15Z |
| format | Article |
| id | doaj.art-b641480d8f434d578981951f966fe13e |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T12:59:15Z |
| publishDate | 2021-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-b641480d8f434d578981951f966fe13e2023-11-21T11:38:32ZengMDPI AGJournal of Clinical Medicine2077-03832021-03-01106132110.3390/jcm10061321Pain Sensitivity, Negative Affect, and Alcohol Use Disorder Status: A Moderated Mediation Study of Emotion DysregulationMaciej Kopera0Elisa M. Trucco1Hubert Suszek2Paweł Kobyliński3Paweł Wiśniewski4Marcin Wojnar5Andrzej Jakubczyk6Department of Psychiatry, Medical University of Warsaw, 00-665 Warsaw, PolandDepartment of Psychology, Center for Children and Families, Florida International University, Miami, FL 33199, USAFaculty of Psychology, University of Warsaw, 00-183 Warsaw, PolandNational Information Processing Institute, Laboratory of Interactive Technologies, 00-608 Warsaw, PolandDepartment of Psychiatry, Medical University of Warsaw, 00-665 Warsaw, PolandDepartment of Psychiatry, Medical University of Warsaw, 00-665 Warsaw, PolandDepartment of Psychiatry, Medical University of Warsaw, 00-665 Warsaw, PolandPrevious work suggests that the association between pain and emotional processes among individuals with alcohol use disorder (AUD) may differ from healthy controls. This study investigates whether pain sensitivity mediates the association between negative affect and emotional dysregulation and whether this association differs across AUD status using moderated mediation. The sample included 165 individuals diagnosed with AUD and 110 healthy controls. Of interest was pain sensitivity, as assessed with the Pain Sensitivity Questionnaire, negative affect, as assessed with the Beck Depression Inventory, and emotional dysregulation, as assessed with the Difficulties in Emotional regulation Scale. Age, biological sex, and current pain severity were included as covariates. The results support a moderated partial mediation model that explained 44% of the variance in emotional dysregulation. The findings indicate that negative affect is related to higher pain sensitivity across groups. Moreover, pain sensitivity partially mediated the association between negative affect and emotional dysregulation, but in opposite directions depending on AUD status. Among healthy controls, greater pain sensitivity was related to better emotional regulation, while greater pain sensitivity led to greater emotional dysregulation among individuals with AUD. The potential parallels in the underlying neurobiological mechanisms of emotionality, pain, and AUD suggest that interventions targeting pain may improve adaptive affect regulation skills, which in turn could reduce negative affect and its effect on pain sensitivity among individuals with AUD.https://www.mdpi.com/2077-0383/10/6/1321alcohol use disorderpain sensitivitynegative affectemotional regulation |
| spellingShingle | Maciej Kopera Elisa M. Trucco Hubert Suszek Paweł Kobyliński Paweł Wiśniewski Marcin Wojnar Andrzej Jakubczyk Pain Sensitivity, Negative Affect, and Alcohol Use Disorder Status: A Moderated Mediation Study of Emotion Dysregulation Journal of Clinical Medicine alcohol use disorder pain sensitivity negative affect emotional regulation |
| title | Pain Sensitivity, Negative Affect, and Alcohol Use Disorder Status: A Moderated Mediation Study of Emotion Dysregulation |
| title_full | Pain Sensitivity, Negative Affect, and Alcohol Use Disorder Status: A Moderated Mediation Study of Emotion Dysregulation |
| title_fullStr | Pain Sensitivity, Negative Affect, and Alcohol Use Disorder Status: A Moderated Mediation Study of Emotion Dysregulation |
| title_full_unstemmed | Pain Sensitivity, Negative Affect, and Alcohol Use Disorder Status: A Moderated Mediation Study of Emotion Dysregulation |
| title_short | Pain Sensitivity, Negative Affect, and Alcohol Use Disorder Status: A Moderated Mediation Study of Emotion Dysregulation |
| title_sort | pain sensitivity negative affect and alcohol use disorder status a moderated mediation study of emotion dysregulation |
| topic | alcohol use disorder pain sensitivity negative affect emotional regulation |
| url | https://www.mdpi.com/2077-0383/10/6/1321 |
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