Acute Type A Dissection during Pregnancy with Marfan's Syndrome
Background Marfan's syndrome (MFS) is a connective tissue disorder, caused by a mutation in the FBN-1 gene and affecting multiple organ systems including the vascular system. During pregnancy, women with MFS have an increased risk of aortic dissection due to changes in the cardiovascular system...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
2021-01-01
|
| Series: | The Thoracic & Cardiovascular Surgeon Reports |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1722705 |
| _version_ | 1818622169910870016 |
|---|---|
| author | Christian Heim Philipp P. Müller Michael Weyand Frank Harig |
| author_facet | Christian Heim Philipp P. Müller Michael Weyand Frank Harig |
| author_sort | Christian Heim |
| collection | DOAJ |
| description | Background Marfan's syndrome (MFS) is a connective tissue disorder, caused by a mutation in the FBN-1 gene and affecting multiple organ systems including the vascular system. During pregnancy, women with MFS have an increased risk of aortic dissection due to changes in the cardiovascular system.
Case Description We present a 39-year-old woman that suffered from an acute aortic dissection in week 33 of her third pregnancy who urgently required lifesaving surgery. Three-dimensional reconstruction of computed tomography scan was performed with unborn child in utero.
Conclusion Monitoring of patients with suspected or confirmed MFS appears essential and interdisciplinary treatment and prevention strategies are required. |
| first_indexed | 2024-12-16T18:20:54Z |
| format | Article |
| id | doaj.art-b647bdaee3ac478d860f29b18a3cfc15 |
| institution | Directory Open Access Journal |
| issn | 2194-7635 2194-7643 |
| language | English |
| last_indexed | 2024-12-16T18:20:54Z |
| publishDate | 2021-01-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | The Thoracic & Cardiovascular Surgeon Reports |
| spelling | doaj.art-b647bdaee3ac478d860f29b18a3cfc152022-12-21T22:21:34ZengGeorg Thieme Verlag KGThe Thoracic & Cardiovascular Surgeon Reports2194-76352194-76432021-01-011001e18e2110.1055/s-0040-1722705Acute Type A Dissection during Pregnancy with Marfan's SyndromeChristian Heim0Philipp P. Müller1Michael Weyand2Frank Harig3Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, GermanyDepartment of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, GermanyDepartment of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, GermanyDepartment of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, GermanyBackground Marfan's syndrome (MFS) is a connective tissue disorder, caused by a mutation in the FBN-1 gene and affecting multiple organ systems including the vascular system. During pregnancy, women with MFS have an increased risk of aortic dissection due to changes in the cardiovascular system. Case Description We present a 39-year-old woman that suffered from an acute aortic dissection in week 33 of her third pregnancy who urgently required lifesaving surgery. Three-dimensional reconstruction of computed tomography scan was performed with unborn child in utero. Conclusion Monitoring of patients with suspected or confirmed MFS appears essential and interdisciplinary treatment and prevention strategies are required.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1722705aortic dissectionmarfanpregnancy |
| spellingShingle | Christian Heim Philipp P. Müller Michael Weyand Frank Harig Acute Type A Dissection during Pregnancy with Marfan's Syndrome The Thoracic & Cardiovascular Surgeon Reports aortic dissection marfan pregnancy |
| title | Acute Type A Dissection during Pregnancy with Marfan's Syndrome |
| title_full | Acute Type A Dissection during Pregnancy with Marfan's Syndrome |
| title_fullStr | Acute Type A Dissection during Pregnancy with Marfan's Syndrome |
| title_full_unstemmed | Acute Type A Dissection during Pregnancy with Marfan's Syndrome |
| title_short | Acute Type A Dissection during Pregnancy with Marfan's Syndrome |
| title_sort | acute type a dissection during pregnancy with marfan s syndrome |
| topic | aortic dissection marfan pregnancy |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1722705 |
| work_keys_str_mv | AT christianheim acutetypeadissectionduringpregnancywithmarfanssyndrome AT philipppmuller acutetypeadissectionduringpregnancywithmarfanssyndrome AT michaelweyand acutetypeadissectionduringpregnancywithmarfanssyndrome AT frankharig acutetypeadissectionduringpregnancywithmarfanssyndrome |