Tobacco carcinogen research to aid understanding of cancer risk and influence policy

Education regarding the health effects associated with tobacco use has made important progress worldwide over the last few decades. Still, tobacco remains a significant cause of cancer and other diseases. As a result, significant worldwide morbidity and mortality is still attributable to tobacco use...

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Main Authors: Hitesh Singhavi, Jasjit S. Ahluwalia, Irina Stepanov, Prakash C. Gupta, Vikram Gota, Pankaj Chaturvedi, Samir S. Khariwala
Format: Article
Language:English
Published: Wiley 2018-10-01
Series:Laryngoscope Investigative Otolaryngology
Subjects:
Online Access:https://doi.org/10.1002/lio2.204
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author Hitesh Singhavi
Jasjit S. Ahluwalia
Irina Stepanov
Prakash C. Gupta
Vikram Gota
Pankaj Chaturvedi
Samir S. Khariwala
author_facet Hitesh Singhavi
Jasjit S. Ahluwalia
Irina Stepanov
Prakash C. Gupta
Vikram Gota
Pankaj Chaturvedi
Samir S. Khariwala
author_sort Hitesh Singhavi
collection DOAJ
description Education regarding the health effects associated with tobacco use has made important progress worldwide over the last few decades. Still, tobacco remains a significant cause of cancer and other diseases. As a result, significant worldwide morbidity and mortality is still attributable to tobacco use in modern times. Research into tobacco products, the carcinogens they contain, and how users metabolize them is an important benefit to the advancement of research aimed at reducing harm associated with tobacco use. This review summarizes the use of this type of research to study tobacco users’ risk of developing cancer, especially head and neck cancer. In addition, we discuss the use of tobacco research to provide support for increasing levels of federal regulation of tobacco products. Level of Evidence 4.
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spelling doaj.art-b64ff8731fe140bc965d3bada18f337c2022-12-21T23:47:54ZengWileyLaryngoscope Investigative Otolaryngology2378-80382018-10-013537237610.1002/lio2.204Tobacco carcinogen research to aid understanding of cancer risk and influence policyHitesh Singhavi0Jasjit S. Ahluwalia1Irina Stepanov2Prakash C. Gupta3Vikram Gota4Pankaj Chaturvedi5Samir S. Khariwala6From the Tata Memorial Centre Mumbai IndiaThe School of Public Health Brown University Providence Rhode Island U.S.A.chool of Public Health Minneapolis Minnesota U.S.A.Healis‐Sekhsaria Institute for Public Health Minneapolis Minnesota U.S.A.From the Tata Memorial Centre Mumbai IndiaFrom the Tata Memorial Centre Mumbai IndiaDepartment of Otolaryngology–Head and Neck Surgery University of Minnesota Minneapolis Minnesota U.S.A.Education regarding the health effects associated with tobacco use has made important progress worldwide over the last few decades. Still, tobacco remains a significant cause of cancer and other diseases. As a result, significant worldwide morbidity and mortality is still attributable to tobacco use in modern times. Research into tobacco products, the carcinogens they contain, and how users metabolize them is an important benefit to the advancement of research aimed at reducing harm associated with tobacco use. This review summarizes the use of this type of research to study tobacco users’ risk of developing cancer, especially head and neck cancer. In addition, we discuss the use of tobacco research to provide support for increasing levels of federal regulation of tobacco products. Level of Evidence 4.https://doi.org/10.1002/lio2.204Head and neck cancertobaccocarcinogennitrosaminesDNA adductLevel of Evidence
spellingShingle Hitesh Singhavi
Jasjit S. Ahluwalia
Irina Stepanov
Prakash C. Gupta
Vikram Gota
Pankaj Chaturvedi
Samir S. Khariwala
Tobacco carcinogen research to aid understanding of cancer risk and influence policy
Laryngoscope Investigative Otolaryngology
Head and neck cancer
tobacco
carcinogen
nitrosamines
DNA adduct
Level of Evidence
title Tobacco carcinogen research to aid understanding of cancer risk and influence policy
title_full Tobacco carcinogen research to aid understanding of cancer risk and influence policy
title_fullStr Tobacco carcinogen research to aid understanding of cancer risk and influence policy
title_full_unstemmed Tobacco carcinogen research to aid understanding of cancer risk and influence policy
title_short Tobacco carcinogen research to aid understanding of cancer risk and influence policy
title_sort tobacco carcinogen research to aid understanding of cancer risk and influence policy
topic Head and neck cancer
tobacco
carcinogen
nitrosamines
DNA adduct
Level of Evidence
url https://doi.org/10.1002/lio2.204
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