TRPV1-Estradiol Stereospecific Relationship Underlies Cell Survival in Oxidative Cell Death

TRPV1-Estradiol Stereospecific Relationship Underlies Cell Survival in Oxidative Cell Death

17β-estradiol is a neuronal survival factor against oxidative stress that triggers its protective effect even in the absence of classical estrogen receptors. The polymodal transient receptor potential vanilloid subtype 1 (TRPV1) channel has been proposed as a steroid receptor implied in tissue prote...

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Bibliographic Details
Main Authors: Ricardo Ramírez-Barrantes, Karina Carvajal-Zamorano, Belen Rodriguez, Claudio Cordova, Carlo Lozano, Felipe Simon, Paula Díaz, Pablo Muñoz, Ivanny Marchant, Ramón Latorre, Karen Castillo, Pablo Olivero
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Physiology
Subjects:
TRPV1
17β-estradiol
cell death
membrane receptor
neuroprotection
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00444/full

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