LORSEN: Fast and Efficient eQTL Mapping With Low Rank Penalized Regression

LORSEN: Fast and Efficient eQTL Mapping With Low Rank Penalized Regression

Characterization of genetic variations that are associated with gene expression levels is essential to understand cellular mechanisms that underline human complex traits. Expression quantitative trait loci (eQTL) mapping attempts to identify genetic variants, such as single nucleotide polymorphisms...

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Bibliographic Details
Main Authors:	Cheng Gao, Hairong Wei, Kui Zhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-11-01
Series:	Frontiers in Genetics
Subjects:	eQTL mapping proximal gradient method cis-eQTL trans-eQTL penalized regression
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2021.690926/full

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