LncRNA HOTAIR is a Prognostic Biomarker for the Proliferation and Chemoresistance of Colorectal Cancer via MiR-203a-3p-Mediated Wnt/ß-Catenin Signaling Pathway

LncRNA HOTAIR is a Prognostic Biomarker for the Proliferation and Chemoresistance of Colorectal Cancer via MiR-203a-3p-Mediated Wnt/ß-Catenin Signaling Pathway

Background/Aims: HOX transcript antisense RNA (HOTAIR) plays a vital role in carcinogenesis. However, its functional and regulatory roles remain unclear. In this study, we aimed to investigate its biological function and clinical significance in human colorectal cancer (CRC). Methods: We examined th...

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Bibliographic Details
Main Authors: Zhigang Xiao, Zhan Qu, Zhikang Chen, Zhixue Fang, Ke Zhou, Zhongcheng Huang, Xiong Guo, Yang Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Colorectal cancer (CRC)
HOX transcript antisense RNA (HOTAIR)
Proliferation
Chemoresistance
Signaling pathway
Online Access:https://www.karger.com/Article/FullText/489110

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