Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs).

Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs).

Recent generation of patient-specific induced pluripotent stem cells (PS-iPSCs) provides significant advantages for cell- and gene-based therapy. Establishment of iPSC-based therapy for skin diseases requires efficient methodology for differentiating iPSCs into both keratinocytes and fibroblasts, th...

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Bibliographic Details
Main Authors: Munenari Itoh, Noriko Umegaki-Arao, Zongyou Guo, Liang Liu, Claire A Higgins, Angela M Christiano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795682?pdf=render

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