Exploring the Potential of β-Catenin <i>O</i>-GlcNAcylation by Using Fluorescence-Based Engineering and Imaging

Exploring the Potential of β-Catenin <i>O</i>-GlcNAcylation by Using Fluorescence-Based Engineering and Imaging

Monitoring glycosylation changes within cells upon response to stimuli remains challenging because of the complexity of this large family of post-translational modifications (PTMs). We developed an original tool, enabling labeling and visualization of the cell cycle key-regulator β-catenin in its &l...

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Bibliographic Details
Main Authors: Angelina Kasprowicz, Corentin Spriet, Christine Terryn, Vincent Rigolot, Stephan Hardiville, Matthew G. Alteen, Tony Lefebvre, Christophe Biot
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
bioorthogonal chemistry
fluorescence
glycosylation
metabolic incorporation
GFP
β-catenin
Online Access:https://www.mdpi.com/1420-3049/25/19/4501

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