Myocardial T2* mapping at ultrahigh magnetic fields: in vivo myocardial tissue characteri-zation and assessment of cardiac physiology with magnetic resonance imaging
Mapping the effective transverse relaxation time T2* represents an emerging MRI tool for non-invasive myocardial tissue characterization and holds the promise to provide means for assessing myocardial (patho)physiology in vivo. This work takes advantage of the linear increase of susceptibility effec...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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De Gruyter
2017-09-01
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| Series: | Current Directions in Biomedical Engineering |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/cdbme-2017-0091 |
| _version_ | 1797848722018664448 |
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| author | Huelnhagen Till Flemming Bert Seeliger Erdmann Schulz-Menger Jeanette Niendorf Thoralf |
| author_facet | Huelnhagen Till Flemming Bert Seeliger Erdmann Schulz-Menger Jeanette Niendorf Thoralf |
| author_sort | Huelnhagen Till |
| collection | DOAJ |
| description | Mapping the effective transverse relaxation time T2* represents an emerging MRI tool for non-invasive myocardial tissue characterization and holds the promise to provide means for assessing myocardial (patho)physiology in vivo. This work takes advantage of the linear increase of susceptibility effects with magnetic field strength which renders it appealing to perform T2* mapping at ultrahigh magnetic fields and enables temporally resolved T2* mapping. Recognizing this potential this study examines the applicability of myocardial CINE T2* mapping in healthy volunteers and hypertrophic cardiomyopathy (HCM) patients at 7.0 Tesla and investigates its capability to distinguish between healthy myocardium and myocardium affected by HCM. |
| first_indexed | 2024-04-09T18:33:19Z |
| format | Article |
| id | doaj.art-b663061cce2a42a58824bf32a2dff528 |
| institution | Directory Open Access Journal |
| issn | 2364-5504 |
| language | English |
| last_indexed | 2024-04-09T18:33:19Z |
| publishDate | 2017-09-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Current Directions in Biomedical Engineering |
| spelling | doaj.art-b663061cce2a42a58824bf32a2dff5282023-04-11T17:07:14ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042017-09-013243343610.1515/cdbme-2017-0091cdbme-2017-0091Myocardial T2* mapping at ultrahigh magnetic fields: in vivo myocardial tissue characteri-zation and assessment of cardiac physiology with magnetic resonance imagingHuelnhagen Till0Flemming Bert1Seeliger Erdmann2Schulz-Menger Jeanette3Niendorf Thoralf4Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Robert-Rössle-Strasse 10, 13125 Berlin, GermanyInstitute for Physiology, Charité University Medicine, Berlin, GermanyInstitute for Physiology, Charité University Medicine, Berlin, GermanyWorking Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max Delbrück Center for Molecular Medicine, Berlin, GermanyBerlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, GermanyMapping the effective transverse relaxation time T2* represents an emerging MRI tool for non-invasive myocardial tissue characterization and holds the promise to provide means for assessing myocardial (patho)physiology in vivo. This work takes advantage of the linear increase of susceptibility effects with magnetic field strength which renders it appealing to perform T2* mapping at ultrahigh magnetic fields and enables temporally resolved T2* mapping. Recognizing this potential this study examines the applicability of myocardial CINE T2* mapping in healthy volunteers and hypertrophic cardiomyopathy (HCM) patients at 7.0 Tesla and investigates its capability to distinguish between healthy myocardium and myocardium affected by HCM.https://doi.org/10.1515/cdbme-2017-0091magnetic resonance imagingmyocardial tissue characterizationphysiologyultrahigh field mr |
| spellingShingle | Huelnhagen Till Flemming Bert Seeliger Erdmann Schulz-Menger Jeanette Niendorf Thoralf Myocardial T2* mapping at ultrahigh magnetic fields: in vivo myocardial tissue characteri-zation and assessment of cardiac physiology with magnetic resonance imaging Current Directions in Biomedical Engineering magnetic resonance imaging myocardial tissue characterization physiology ultrahigh field mr |
| title | Myocardial T2* mapping at ultrahigh magnetic fields: in vivo myocardial tissue characteri-zation and assessment of cardiac physiology with magnetic resonance imaging |
| title_full | Myocardial T2* mapping at ultrahigh magnetic fields: in vivo myocardial tissue characteri-zation and assessment of cardiac physiology with magnetic resonance imaging |
| title_fullStr | Myocardial T2* mapping at ultrahigh magnetic fields: in vivo myocardial tissue characteri-zation and assessment of cardiac physiology with magnetic resonance imaging |
| title_full_unstemmed | Myocardial T2* mapping at ultrahigh magnetic fields: in vivo myocardial tissue characteri-zation and assessment of cardiac physiology with magnetic resonance imaging |
| title_short | Myocardial T2* mapping at ultrahigh magnetic fields: in vivo myocardial tissue characteri-zation and assessment of cardiac physiology with magnetic resonance imaging |
| title_sort | myocardial t2 mapping at ultrahigh magnetic fields in vivo myocardial tissue characteri zation and assessment of cardiac physiology with magnetic resonance imaging |
| topic | magnetic resonance imaging myocardial tissue characterization physiology ultrahigh field mr |
| url | https://doi.org/10.1515/cdbme-2017-0091 |
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