Precipitated withdrawal with kratom use following naltrexone administration
Kratom is an herbal supplement with reports of use for natural pain relief or treatment of opioid withdrawal symptoms. Kratom has metabolites that bind to and agonize mu-opioid receptors similar to opiate medications. There have been reports of serious adverse reactions, with a potential for depende...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Association of Psychiatric Pharmacists
2023-06-01
|
| Series: | Mental Health Clinician |
| Subjects: | |
| Online Access: | https://theijpt.org/doi/pdf/10.9740/mhc.2023.06.155 |
| _version_ | 1827576868649304064 |
|---|---|
| author | Jarka Courtney PharmD, BCPS, BCPP Gregoire Kelsey PharmD, BCCCP |
| author_facet | Jarka Courtney PharmD, BCPS, BCPP Gregoire Kelsey PharmD, BCCCP |
| author_sort | Jarka Courtney PharmD, BCPS, BCPP |
| collection | DOAJ |
| description | Kratom is an herbal supplement with reports of use for natural pain relief or treatment of opioid withdrawal symptoms. Kratom has metabolites that bind to and agonize mu-opioid receptors similar to opiate medications. There have been reports of serious adverse reactions, with a potential for dependence with long-term use and withdrawal that may occur upon discontinuation. Naltrexone can result in abrupt withdrawal symptoms when used with opioids or opioid-like supplements such as kratom. This case report describes withdrawal precipitated by naltrexone administration in a patient with undisclosed chronic kratom use. This case highlights the importance of thorough assessment of all self-administered herbal and over-the-counter supplements as they may have serious interactions with other prescribed medications and affect therapeutic outcomes. |
| first_indexed | 2024-03-08T21:18:40Z |
| format | Article |
| id | doaj.art-b6676ea739eb42aea81635e7318986e9 |
| institution | Directory Open Access Journal |
| issn | 2168-9709 |
| language | English |
| last_indexed | 2024-03-08T21:18:40Z |
| publishDate | 2023-06-01 |
| publisher | American Association of Psychiatric Pharmacists |
| record_format | Article |
| series | Mental Health Clinician |
| spelling | doaj.art-b6676ea739eb42aea81635e7318986e92023-12-21T12:17:09ZengAmerican Association of Psychiatric PharmacistsMental Health Clinician2168-97092023-06-0113315515810.9740/mhc.2023.06.155i2168-9709-13-3-155Precipitated withdrawal with kratom use following naltrexone administrationJarka Courtney PharmD, BCPS, BCPP0https://orcid.org/0000-0002-8815-9221Gregoire Kelsey PharmD, BCCCP1https://orcid.org/0000-0003-3285-91621 Clinical Pharmacy Specialist Behavioral Health, Catholic Health System, Mount St. Mary’s Hospital, Lewiston, New York2 Clinical Pharmacy Specialist Critical Care, Catholic Health System, Kenmore Mercy Hospital, Kenmore, New YorkKratom is an herbal supplement with reports of use for natural pain relief or treatment of opioid withdrawal symptoms. Kratom has metabolites that bind to and agonize mu-opioid receptors similar to opiate medications. There have been reports of serious adverse reactions, with a potential for dependence with long-term use and withdrawal that may occur upon discontinuation. Naltrexone can result in abrupt withdrawal symptoms when used with opioids or opioid-like supplements such as kratom. This case report describes withdrawal precipitated by naltrexone administration in a patient with undisclosed chronic kratom use. This case highlights the importance of thorough assessment of all self-administered herbal and over-the-counter supplements as they may have serious interactions with other prescribed medications and affect therapeutic outcomes.https://theijpt.org/doi/pdf/10.9740/mhc.2023.06.155kratommitragynanaltrexonewithdrawal |
| spellingShingle | Jarka Courtney PharmD, BCPS, BCPP Gregoire Kelsey PharmD, BCCCP Precipitated withdrawal with kratom use following naltrexone administration Mental Health Clinician kratom mitragyna naltrexone withdrawal |
| title | Precipitated withdrawal with kratom use following naltrexone administration |
| title_full | Precipitated withdrawal with kratom use following naltrexone administration |
| title_fullStr | Precipitated withdrawal with kratom use following naltrexone administration |
| title_full_unstemmed | Precipitated withdrawal with kratom use following naltrexone administration |
| title_short | Precipitated withdrawal with kratom use following naltrexone administration |
| title_sort | precipitated withdrawal with kratom use following naltrexone administration |
| topic | kratom mitragyna naltrexone withdrawal |
| url | https://theijpt.org/doi/pdf/10.9740/mhc.2023.06.155 |
| work_keys_str_mv | AT jarkacourtneypharmdbcpsbcpp precipitatedwithdrawalwithkratomusefollowingnaltrexoneadministration AT gregoirekelseypharmdbcccp precipitatedwithdrawalwithkratomusefollowingnaltrexoneadministration |