Micrometastasis: Neglected enough!
Oral cancer, being the sixth most common cancer in the world, accounts for approximately 13% of deaths worldwide. Metastasis to the lymph nodes is one of the major prognostic factor for oral cancer. Micrometastasis are microscopic deposits of malignant cells lodged in lymph nodes. Tumor recurrence u...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Journal of Indian Academy of Oral Medicine and Radiology |
| Subjects: | |
| Online Access: | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2017;volume=29;issue=2;spage=111;epage=114;aulast=Chavva |
| _version_ | 1818562096729686016 |
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| author | Prathyusha Chavva Devaraju Devaiah Vijeev Vasudevan Manjunath Venkatappa |
| author_facet | Prathyusha Chavva Devaraju Devaiah Vijeev Vasudevan Manjunath Venkatappa |
| author_sort | Prathyusha Chavva |
| collection | DOAJ |
| description | Oral cancer, being the sixth most common cancer in the world, accounts for approximately 13% of deaths worldwide. Metastasis to the lymph nodes is one of the major prognostic factor for oral cancer. Micrometastasis are microscopic deposits of malignant cells lodged in lymph nodes. Tumor recurrence usually reflects the presence of such deposits which cannot be detected initially by conventional methods. Early screening of such cells using immunological and molecular markers would help in better staging of the primary tumor followed by prompt treatment, thus reducing tumor relapse. Therefore, the concept of micrometastasis has resulted in a paradigm shift in the staging of epithelial tumors and the overall understanding of the malignant process. |
| first_indexed | 2024-12-14T00:59:13Z |
| format | Article |
| id | doaj.art-b669f2037eaa4f718753303798f742d3 |
| institution | Directory Open Access Journal |
| issn | 0972-1363 |
| language | English |
| last_indexed | 2024-12-14T00:59:13Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Academy of Oral Medicine and Radiology |
| spelling | doaj.art-b669f2037eaa4f718753303798f742d32022-12-21T23:23:22ZengWolters Kluwer Medknow PublicationsJournal of Indian Academy of Oral Medicine and Radiology0972-13632017-01-0129211111410.4103/jiaomr.JIAOMR_53_16Micrometastasis: Neglected enough!Prathyusha ChavvaDevaraju DevaiahVijeev VasudevanManjunath VenkatappaOral cancer, being the sixth most common cancer in the world, accounts for approximately 13% of deaths worldwide. Metastasis to the lymph nodes is one of the major prognostic factor for oral cancer. Micrometastasis are microscopic deposits of malignant cells lodged in lymph nodes. Tumor recurrence usually reflects the presence of such deposits which cannot be detected initially by conventional methods. Early screening of such cells using immunological and molecular markers would help in better staging of the primary tumor followed by prompt treatment, thus reducing tumor relapse. Therefore, the concept of micrometastasis has resulted in a paradigm shift in the staging of epithelial tumors and the overall understanding of the malignant process.http://www.jiaomr.in/article.asp?issn=0972-1363;year=2017;volume=29;issue=2;spage=111;epage=114;aulast=ChavvaMolecular detectionoral field cancerizationsentinel lymph nodetumor staging |
| spellingShingle | Prathyusha Chavva Devaraju Devaiah Vijeev Vasudevan Manjunath Venkatappa Micrometastasis: Neglected enough! Journal of Indian Academy of Oral Medicine and Radiology Molecular detection oral field cancerization sentinel lymph node tumor staging |
| title | Micrometastasis: Neglected enough! |
| title_full | Micrometastasis: Neglected enough! |
| title_fullStr | Micrometastasis: Neglected enough! |
| title_full_unstemmed | Micrometastasis: Neglected enough! |
| title_short | Micrometastasis: Neglected enough! |
| title_sort | micrometastasis neglected enough |
| topic | Molecular detection oral field cancerization sentinel lymph node tumor staging |
| url | http://www.jiaomr.in/article.asp?issn=0972-1363;year=2017;volume=29;issue=2;spage=111;epage=114;aulast=Chavva |
| work_keys_str_mv | AT prathyushachavva micrometastasisneglectedenough AT devarajudevaiah micrometastasisneglectedenough AT vijeevvasudevan micrometastasisneglectedenough AT manjunathvenkatappa micrometastasisneglectedenough |