Impact of Anticipated Awake Surgery on Psychooncological Distress in Brain Tumor Patients
BackgroundBrain tumor patients present high rates of distress, anxiety, and depression, in particular perioperatively. For resection of eloquent located cerebral lesions, awake surgery is the gold standard surgical method for the preservation of speech and motor function, which might be accompanied...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-01-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2021.795247/full |
| _version_ | 1828138432846626816 |
|---|---|
| author | Franziska Staub-Bartelt Oliver Radtke Daniel Hänggi Michael Sabel Marion Rapp |
| author_facet | Franziska Staub-Bartelt Oliver Radtke Daniel Hänggi Michael Sabel Marion Rapp |
| author_sort | Franziska Staub-Bartelt |
| collection | DOAJ |
| description | BackgroundBrain tumor patients present high rates of distress, anxiety, and depression, in particular perioperatively. For resection of eloquent located cerebral lesions, awake surgery is the gold standard surgical method for the preservation of speech and motor function, which might be accompanied by increased psychological distress. The aim of the present study was to analyze if patients who are undergoing awake craniotomy suffer from increased prevalence or higher scores in distress, anxiety, or depression.MethodsPatients, who were electively admitted for brain tumor surgery at our neurooncological department, were perioperatively screened regarding distress, anxiety, and quality of life using three established self-assessment instruments (Hospital Anxiety and Depression Scale, distress thermometer, and European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30-BN20). Screening results were correlated regarding operation technique (awake vs. general anesthesia). Retrospective statistical analyses for nominal variables were conducted using chi-square test. Metric variables were analyzed using the Kruskal–Wallis test, the Mann–Whitney U-test, and independent-samples t-tests.ResultsData from 54 patients (26 male and 28 female) aged 29 to 82 years were available for statistical analyses. A total of 37 patients received primary resection and 17 recurrent tumor resection. Awake surgery was performed in 35 patients. There was no significant difference in awake versus non-awake surgery patients regarding prevalence (of distress (p = 0.465), anxiety (p = 0.223), or depression (p = 0.882). Furthermore, awake surgery had no significant influence on distress thermometer score (p = 0.668), anxiety score (p = 0.682), or depression score (p = 0.630) as well as future uncertainty (p = 0.436) or global health status (p = 0.943). Additionally, analyses revealed that primary or recurrent surgery also did not have any significant influence on the prevalence or scoring of the evaluated items.ConclusionAnalyses of our cohort’s data suggest that planned awake surgery might not have a negative impact on patients concerning the prevalence and severity of manifestation of distress, anxiety, or depression in psychooncological screening. Patients undergoing recurrent surgery tend to demonstrate increased distress, although results were not significant. |
| first_indexed | 2024-04-11T18:35:48Z |
| format | Article |
| id | doaj.art-b66ca239b3314867a66485acaeb92575 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-11T18:35:48Z |
| publishDate | 2022-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-b66ca239b3314867a66485acaeb925752022-12-22T04:09:17ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-01-011110.3389/fonc.2021.795247795247Impact of Anticipated Awake Surgery on Psychooncological Distress in Brain Tumor PatientsFranziska Staub-BarteltOliver RadtkeDaniel HänggiMichael SabelMarion RappBackgroundBrain tumor patients present high rates of distress, anxiety, and depression, in particular perioperatively. For resection of eloquent located cerebral lesions, awake surgery is the gold standard surgical method for the preservation of speech and motor function, which might be accompanied by increased psychological distress. The aim of the present study was to analyze if patients who are undergoing awake craniotomy suffer from increased prevalence or higher scores in distress, anxiety, or depression.MethodsPatients, who were electively admitted for brain tumor surgery at our neurooncological department, were perioperatively screened regarding distress, anxiety, and quality of life using three established self-assessment instruments (Hospital Anxiety and Depression Scale, distress thermometer, and European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30-BN20). Screening results were correlated regarding operation technique (awake vs. general anesthesia). Retrospective statistical analyses for nominal variables were conducted using chi-square test. Metric variables were analyzed using the Kruskal–Wallis test, the Mann–Whitney U-test, and independent-samples t-tests.ResultsData from 54 patients (26 male and 28 female) aged 29 to 82 years were available for statistical analyses. A total of 37 patients received primary resection and 17 recurrent tumor resection. Awake surgery was performed in 35 patients. There was no significant difference in awake versus non-awake surgery patients regarding prevalence (of distress (p = 0.465), anxiety (p = 0.223), or depression (p = 0.882). Furthermore, awake surgery had no significant influence on distress thermometer score (p = 0.668), anxiety score (p = 0.682), or depression score (p = 0.630) as well as future uncertainty (p = 0.436) or global health status (p = 0.943). Additionally, analyses revealed that primary or recurrent surgery also did not have any significant influence on the prevalence or scoring of the evaluated items.ConclusionAnalyses of our cohort’s data suggest that planned awake surgery might not have a negative impact on patients concerning the prevalence and severity of manifestation of distress, anxiety, or depression in psychooncological screening. Patients undergoing recurrent surgery tend to demonstrate increased distress, although results were not significant.https://www.frontiersin.org/articles/10.3389/fonc.2021.795247/fullawake surgerypsychooncological distressglioblastomabrain tumorHADSEORT C QLQ-C30 |
| spellingShingle | Franziska Staub-Bartelt Oliver Radtke Daniel Hänggi Michael Sabel Marion Rapp Impact of Anticipated Awake Surgery on Psychooncological Distress in Brain Tumor Patients Frontiers in Oncology awake surgery psychooncological distress glioblastoma brain tumor HADS EORT C QLQ-C30 |
| title | Impact of Anticipated Awake Surgery on Psychooncological Distress in Brain Tumor Patients |
| title_full | Impact of Anticipated Awake Surgery on Psychooncological Distress in Brain Tumor Patients |
| title_fullStr | Impact of Anticipated Awake Surgery on Psychooncological Distress in Brain Tumor Patients |
| title_full_unstemmed | Impact of Anticipated Awake Surgery on Psychooncological Distress in Brain Tumor Patients |
| title_short | Impact of Anticipated Awake Surgery on Psychooncological Distress in Brain Tumor Patients |
| title_sort | impact of anticipated awake surgery on psychooncological distress in brain tumor patients |
| topic | awake surgery psychooncological distress glioblastoma brain tumor HADS EORT C QLQ-C30 |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2021.795247/full |
| work_keys_str_mv | AT franziskastaubbartelt impactofanticipatedawakesurgeryonpsychooncologicaldistressinbraintumorpatients AT oliverradtke impactofanticipatedawakesurgeryonpsychooncologicaldistressinbraintumorpatients AT danielhanggi impactofanticipatedawakesurgeryonpsychooncologicaldistressinbraintumorpatients AT michaelsabel impactofanticipatedawakesurgeryonpsychooncologicaldistressinbraintumorpatients AT marionrapp impactofanticipatedawakesurgeryonpsychooncologicaldistressinbraintumorpatients |