Parameters oxidative stress and endogenous intoxication of peripheral blood in patients with exogenous organic disorders in dynamic of the pharmacotherapy

Complex clinical-biological investigation has been conducted in 25 patients with exogenous organic disorders and 30 mentally and physically healthy persons. Influence of the metabolic cerebroprotector cortexin on indices of oxidative stress in dynamic of the pharmacotherapy has been investigated. It...

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Main Authors: N. M. Krotenko, A. S. Boiko, Ye. M. Yepanchintseva, S. A. Ivanova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2012-02-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/427
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author N. M. Krotenko
A. S. Boiko
Ye. M. Yepanchintseva
S. A. Ivanova
author_facet N. M. Krotenko
A. S. Boiko
Ye. M. Yepanchintseva
S. A. Ivanova
author_sort N. M. Krotenko
collection DOAJ
description Complex clinical-biological investigation has been conducted in 25 patients with exogenous organic disorders and 30 mentally and physically healthy persons. Influence of the metabolic cerebroprotector cortexin on indices of oxidative stress in dynamic of the pharmacotherapy has been investigated. It has been shown that cortexin increases clinical efficacy of complex therapy of patients and exerts positive influence on indices of homeostatic systems. Action of cortexin on indices of the oxidative stress is characterised by normalisation of the processes of peroxide oxidation of lipids in erythrocytes and in serum
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spelling doaj.art-b66e0b36d1bd407c9e3568cff827b3762023-03-13T09:58:16ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842012-02-0111117918410.20538/1682-0363-2012-1-179-184405Parameters oxidative stress and endogenous intoxication of peripheral blood in patients with exogenous organic disorders in dynamic of the pharmacotherapyN. M. Krotenko0A. S. Boiko1Ye. M. Yepanchintseva2S. A. Ivanova3Сибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскНИИ психического здоровья СО РАМН, г. ТомскНИИ психического здоровья СО РАМН, г. ТомскComplex clinical-biological investigation has been conducted in 25 patients with exogenous organic disorders and 30 mentally and physically healthy persons. Influence of the metabolic cerebroprotector cortexin on indices of oxidative stress in dynamic of the pharmacotherapy has been investigated. It has been shown that cortexin increases clinical efficacy of complex therapy of patients and exerts positive influence on indices of homeostatic systems. Action of cortexin on indices of the oxidative stress is characterised by normalisation of the processes of peroxide oxidation of lipids in erythrocytes and in serumhttps://bulletin.ssmu.ru/jour/article/view/427кортексинэкзогенно-органические расстройстваэндогенная интоксикацияокислительный стресскаталаза
spellingShingle N. M. Krotenko
A. S. Boiko
Ye. M. Yepanchintseva
S. A. Ivanova
Parameters oxidative stress and endogenous intoxication of peripheral blood in patients with exogenous organic disorders in dynamic of the pharmacotherapy
Бюллетень сибирской медицины
кортексин
экзогенно-органические расстройства
эндогенная интоксикация
окислительный стресс
каталаза
title Parameters oxidative stress and endogenous intoxication of peripheral blood in patients with exogenous organic disorders in dynamic of the pharmacotherapy
title_full Parameters oxidative stress and endogenous intoxication of peripheral blood in patients with exogenous organic disorders in dynamic of the pharmacotherapy
title_fullStr Parameters oxidative stress and endogenous intoxication of peripheral blood in patients with exogenous organic disorders in dynamic of the pharmacotherapy
title_full_unstemmed Parameters oxidative stress and endogenous intoxication of peripheral blood in patients with exogenous organic disorders in dynamic of the pharmacotherapy
title_short Parameters oxidative stress and endogenous intoxication of peripheral blood in patients with exogenous organic disorders in dynamic of the pharmacotherapy
title_sort parameters oxidative stress and endogenous intoxication of peripheral blood in patients with exogenous organic disorders in dynamic of the pharmacotherapy
topic кортексин
экзогенно-органические расстройства
эндогенная интоксикация
окислительный стресс
каталаза
url https://bulletin.ssmu.ru/jour/article/view/427
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AT yemyepanchintseva parametersoxidativestressandendogenousintoxicationofperipheralbloodinpatientswithexogenousorganicdisordersindynamicofthepharmacotherapy
AT saivanova parametersoxidativestressandendogenousintoxicationofperipheralbloodinpatientswithexogenousorganicdisordersindynamicofthepharmacotherapy