pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production.

pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production.

Inflammatory factors and type I interferons (IFNs) are key components of host antiviral innate immune responses, which can be released from the pathogen-infected macrophages. African swine fever virus (ASFV) has developed various strategies to evade host antiviral innate immune responses, including...

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Bibliographic Details
Main Authors: Jiangnan Li, Jie Song, Li Kang, Li Huang, Shijun Zhou, Liang Hu, Jun Zheng, Changyao Li, Xianfeng Zhang, Xijun He, Dongming Zhao, Zhigao Bu, Changjiang Weng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009733

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