Investigation of the Antibacterial Effect of Venom of the Iranian Snake Echis carinatus
Although some venoms and their isolated compounds have been shown to have antibacterial properties, most have not been investigated for such activity. Echis carinatus is one of the most venomous snakes in the world and has an effective haematotoxic venom that destroys endothelial cells and causes ha...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ferdowsi University of Mashhad
2010-09-01
|
| Series: | The Iranian Journal of Veterinary Science and Technology |
| Subjects: | |
| Online Access: | https://ijvst.um.ac.ir/article_25523_6be06863f5f0bfb55c1924e289393770.pdf |
| _version_ | 1828399919592898560 |
|---|---|
| author | Atena Jami al ahmadi Behrooz Fathi Abdoula Jamshidi Hosein Zolfagharian Abbase Zare Mirakabbadi |
| author_facet | Atena Jami al ahmadi Behrooz Fathi Abdoula Jamshidi Hosein Zolfagharian Abbase Zare Mirakabbadi |
| author_sort | Atena Jami al ahmadi |
| collection | DOAJ |
| description | Although some venoms and their isolated compounds have been shown to have antibacterial properties, most have not been investigated for such activity. Echis carinatus is one of the most venomous snakes in the world and has an effective haematotoxic venom that destroys endothelial cells and causes haemorrhagia.
In this study, the antibacterial activity of Iranian snake Echis carinatus venom against six different bacteria (Staphylococcus aureus, Methicillin Resistant Staphylococcus aureus (MRSA), Listeria monocytogenes, Bacillus subtilis, Salmonella typhimurium and Escherichia coli O157:H7), were investigated. Crude venom (100µg/ml) and different standard antibiotic disks as positive controls were tested by the gel diffusion method. Since the results showed that Echis carinatus venom has a significant antibacterial effect against S. aureus and MRSA, the minimum inhibitory concentrations (MIC) were also determined for these two susceptible bacteria: this was 80µg ml-1 against both strains. Also, the results determined that Echis carinatus venom dose not have a noticeable effect on other tested bacteria. |
| first_indexed | 2024-12-10T09:24:13Z |
| format | Article |
| id | doaj.art-b6757529616b4b048bf2b31f7ba3be79 |
| institution | Directory Open Access Journal |
| issn | 2008-465X 2423-6306 |
| language | English |
| last_indexed | 2024-12-10T09:24:13Z |
| publishDate | 2010-09-01 |
| publisher | Ferdowsi University of Mashhad |
| record_format | Article |
| series | The Iranian Journal of Veterinary Science and Technology |
| spelling | doaj.art-b6757529616b4b048bf2b31f7ba3be792022-12-22T01:54:36ZengFerdowsi University of MashhadThe Iranian Journal of Veterinary Science and Technology2008-465X2423-63062010-09-0122939910.22067/veterinary.v2i2.836925523Investigation of the Antibacterial Effect of Venom of the Iranian Snake Echis carinatusAtena Jami al ahmadi0Behrooz Fathi1Abdoula Jamshidi2Hosein Zolfagharian3Abbase Zare Mirakabbadi4Ferdowsi University of MashhadFerdowsi University of MashhadFerdowsi University of MashhadRazi Vaccine and Serum Research InstituteRazi Vaccine and Serum Research InstituteAlthough some venoms and their isolated compounds have been shown to have antibacterial properties, most have not been investigated for such activity. Echis carinatus is one of the most venomous snakes in the world and has an effective haematotoxic venom that destroys endothelial cells and causes haemorrhagia. In this study, the antibacterial activity of Iranian snake Echis carinatus venom against six different bacteria (Staphylococcus aureus, Methicillin Resistant Staphylococcus aureus (MRSA), Listeria monocytogenes, Bacillus subtilis, Salmonella typhimurium and Escherichia coli O157:H7), were investigated. Crude venom (100µg/ml) and different standard antibiotic disks as positive controls were tested by the gel diffusion method. Since the results showed that Echis carinatus venom has a significant antibacterial effect against S. aureus and MRSA, the minimum inhibitory concentrations (MIC) were also determined for these two susceptible bacteria: this was 80µg ml-1 against both strains. Also, the results determined that Echis carinatus venom dose not have a noticeable effect on other tested bacteria.https://ijvst.um.ac.ir/article_25523_6be06863f5f0bfb55c1924e289393770.pdfantibacterialvenomechis carinatus |
| spellingShingle | Atena Jami al ahmadi Behrooz Fathi Abdoula Jamshidi Hosein Zolfagharian Abbase Zare Mirakabbadi Investigation of the Antibacterial Effect of Venom of the Iranian Snake Echis carinatus The Iranian Journal of Veterinary Science and Technology antibacterial venom echis carinatus |
| title | Investigation of the Antibacterial Effect of Venom of the Iranian Snake Echis carinatus |
| title_full | Investigation of the Antibacterial Effect of Venom of the Iranian Snake Echis carinatus |
| title_fullStr | Investigation of the Antibacterial Effect of Venom of the Iranian Snake Echis carinatus |
| title_full_unstemmed | Investigation of the Antibacterial Effect of Venom of the Iranian Snake Echis carinatus |
| title_short | Investigation of the Antibacterial Effect of Venom of the Iranian Snake Echis carinatus |
| title_sort | investigation of the antibacterial effect of venom of the iranian snake echis carinatus |
| topic | antibacterial venom echis carinatus |
| url | https://ijvst.um.ac.ir/article_25523_6be06863f5f0bfb55c1924e289393770.pdf |
| work_keys_str_mv | AT atenajamialahmadi investigationoftheantibacterialeffectofvenomoftheiraniansnakeechiscarinatus AT behroozfathi investigationoftheantibacterialeffectofvenomoftheiraniansnakeechiscarinatus AT abdoulajamshidi investigationoftheantibacterialeffectofvenomoftheiraniansnakeechiscarinatus AT hoseinzolfagharian investigationoftheantibacterialeffectofvenomoftheiraniansnakeechiscarinatus AT abbasezaremirakabbadi investigationoftheantibacterialeffectofvenomoftheiraniansnakeechiscarinatus |