Amino Acid Derivatives of Ginsenoside AD-2 Induce HepG2 Cell Apoptosis by Affecting the Cytoskeleton

Amino Acid Derivatives of Ginsenoside AD-2 Induce HepG2 Cell Apoptosis by Affecting the Cytoskeleton

<b>AD-2</b> (20(R)-dammarane-3β, 12β, 20, 25-tetrol, 25-OH-PPD) was structurally modified to introduce additional amino groups, which can better exert its anti-tumor effects in MCF-7, A549, LoVo, HCT-116, HT -29, and U-87 cell lines. We investigated the cellular activity of 15 different...

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Bibliographic Details
Main Authors: Lizhen Lin, Yuqing Zhao, Peng Wang, Tao Li, Yuhang Liang, Yu Chen, Xianyi Meng, Yudong Zhang, Guangyue Su
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Molecules
Subjects:
<b>AD-2</b>
amino acid derivatives
apoptosis
cytotoxic
dammarane triterpene
Online Access:https://www.mdpi.com/1420-3049/28/21/7400

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