Integrin Crosstalk Contributes to the Complexity of Signalling and Unpredictable Cancer Cell Fates

Integrin Crosstalk Contributes to the Complexity of Signalling and Unpredictable Cancer Cell Fates

Integrins are heterodimeric cell surface receptors composed of α and β subunits that control adhesion, proliferation and gene expression. The integrin heterodimer binding to ligand reorganises the cytoskeletal networks and triggers multiple signalling pathways that can cause changes in cell cycle, p...

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Bibliographic Details
Main Authors: Ivana Samaržija, Ana Dekanić, Jonathan D. Humphries, Mladen Paradžik, Nikolina Stojanović, Martin J. Humphries, Andreja Ambriović-Ristov
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
integrin
integrin adhesion complexes
integrin crosstalk
integrin switching
cancer
Online Access:https://www.mdpi.com/2072-6694/12/7/1910

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