Synaptic responses in superficial layers of medial entorhinal cortex from rats with kainate-induced epilepsy

Synaptic responses in superficial layers of medial entorhinal cortex from rats with kainate-induced epilepsy

Mesial temporal lobe epilepsy patients often display shrinkage of the entorhinal cortex, which has been attributed to neuronal loss in medial entorhinal cortex layer III (MEC-III). MEC-III neuronal loss is reproduced in chronic epileptic rats after kainate-induced (KA) status epilepticus. Here we ex...

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Bibliographic Details
Main Authors: Else A. Tolner, Christiane Frahm, Robert Metzger, Jan A. Gorter, Otto W. Witte, Fernando H. Lopes da Silva, Uwe Heinemann
Format: Article
Language:English
Published: Elsevier 2007-05-01
Series:Neurobiology of Disease
Subjects:
Epileptogenesis
Cell loss
Presubiculum
Disinhibition
GAD65/67-hyperexcitability
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107000290

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