Synthesis of novel organic intermediate substituted pyrazole ethyl formate and pyrazolecarboxylic acid(新型有机中间体取代吡唑甲酸乙酯、取代吡唑甲酸的合成)
吡唑类化合物是一类具有广泛生物活性的杂环化合物，在医药和农药领域均有商品化的品种问世.在寻找新的吡唑类化合物的过程中，以草酸二乙酯为起始原料，分别与不同的一元酮反应，经过缩合、环合、烷基化、（溴化）、水解，合成了a~d 4个未见文献报道的取代吡唑甲酸乙酯、取代吡唑甲酸中间体，收率78%~90%，结构均经元素分析、1H NMR、MS和IR确证，...
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| Format: | Article |
| Language: | zho |
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Zhejiang University Press
2008-11-01
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| Series: | Zhejiang Daxue xuebao. Lixue ban |
| Subjects: | |
| Online Access: | https://doi.org/10.3785/j.issn.1008-9497.2008.06.012 |
| _version_ | 1827303313757962240 |
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| author | TUMei-ling(屠美玲) XIABo(夏波) ZHENGMin(郑敏) SHENDe-long(沈德隆) |
| author_facet | TUMei-ling(屠美玲) XIABo(夏波) ZHENGMin(郑敏) SHENDe-long(沈德隆) |
| author_sort | TUMei-ling(屠美玲) |
| collection | DOAJ |
| description | 吡唑类化合物是一类具有广泛生物活性的杂环化合物，在医药和农药领域均有商品化的品种问世.在寻找新的吡唑类化合物的过程中，以草酸二乙酯为起始原料，分别与不同的一元酮反应，经过缩合、环合、烷基化、（溴化）、水解，合成了a~d 4个未见文献报道的取代吡唑甲酸乙酯、取代吡唑甲酸中间体，收率78%~90%，结构均经元素分析、1H NMR、MS和IR确证， |
| first_indexed | 2024-04-24T16:59:43Z |
| format | Article |
| id | doaj.art-b6814b933fca452cbe2ddc566d162c90 |
| institution | Directory Open Access Journal |
| issn | 1008-9497 |
| language | zho |
| last_indexed | 2024-04-24T16:59:43Z |
| publishDate | 2008-11-01 |
| publisher | Zhejiang University Press |
| record_format | Article |
| series | Zhejiang Daxue xuebao. Lixue ban |
| spelling | doaj.art-b6814b933fca452cbe2ddc566d162c902024-03-29T01:58:26ZzhoZhejiang University PressZhejiang Daxue xuebao. Lixue ban1008-94972008-11-0135664164310.3785/j.issn.1008-9497.2008.06.012Synthesis of novel organic intermediate substituted pyrazole ethyl formate and pyrazolecarboxylic acid(新型有机中间体取代吡唑甲酸乙酯、取代吡唑甲酸的合成)TUMei-ling(屠美玲)0XIABo(夏波)1ZHENGMin(郑敏)2SHENDe-long(沈德隆)3Pesticide Research Institute, Zhejiang University of Technology, Hangzhou 310014, China(浙江工业大学农药研究所，浙江 杭州 310014)Pesticide Research Institute, Zhejiang University of Technology, Hangzhou 310014, China(浙江工业大学农药研究所，浙江 杭州 310014)Pesticide Research Institute, Zhejiang University of Technology, Hangzhou 310014, China(浙江工业大学农药研究所，浙江 杭州 310014)Pesticide Research Institute, Zhejiang University of Technology, Hangzhou 310014, China(浙江工业大学农药研究所，浙江 杭州 310014)吡唑类化合物是一类具有广泛生物活性的杂环化合物，在医药和农药领域均有商品化的品种问世.在寻找新的吡唑类化合物的过程中，以草酸二乙酯为起始原料，分别与不同的一元酮反应，经过缩合、环合、烷基化、（溴化）、水解，合成了a~d 4个未见文献报道的取代吡唑甲酸乙酯、取代吡唑甲酸中间体，收率78%~90%，结构均经元素分析、1H NMR、MS和IR确证，https://doi.org/10.3785/j.issn.1008-9497.2008.06.012吡唑甲酸乙酯吡唑甲酸中间体合成 |
| spellingShingle | TUMei-ling(屠美玲) XIABo(夏波) ZHENGMin(郑敏) SHENDe-long(沈德隆) Synthesis of novel organic intermediate substituted pyrazole ethyl formate and pyrazolecarboxylic acid(新型有机中间体取代吡唑甲酸乙酯、取代吡唑甲酸的合成) Zhejiang Daxue xuebao. Lixue ban 吡唑甲酸乙酯 吡唑甲酸 中间体 合成 |
| title | Synthesis of novel organic intermediate substituted pyrazole ethyl formate and pyrazolecarboxylic acid(新型有机中间体取代吡唑甲酸乙酯、取代吡唑甲酸的合成) |
| title_full | Synthesis of novel organic intermediate substituted pyrazole ethyl formate and pyrazolecarboxylic acid(新型有机中间体取代吡唑甲酸乙酯、取代吡唑甲酸的合成) |
| title_fullStr | Synthesis of novel organic intermediate substituted pyrazole ethyl formate and pyrazolecarboxylic acid(新型有机中间体取代吡唑甲酸乙酯、取代吡唑甲酸的合成) |
| title_full_unstemmed | Synthesis of novel organic intermediate substituted pyrazole ethyl formate and pyrazolecarboxylic acid(新型有机中间体取代吡唑甲酸乙酯、取代吡唑甲酸的合成) |
| title_short | Synthesis of novel organic intermediate substituted pyrazole ethyl formate and pyrazolecarboxylic acid(新型有机中间体取代吡唑甲酸乙酯、取代吡唑甲酸的合成) |
| title_sort | synthesis of novel organic intermediate substituted pyrazole ethyl formate and pyrazolecarboxylic acid 新型有机中间体取代吡唑甲酸乙酯 取代吡唑甲酸的合成 |
| topic | 吡唑甲酸乙酯 吡唑甲酸 中间体 合成 |
| url | https://doi.org/10.3785/j.issn.1008-9497.2008.06.012 |
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