A holistic evolutionary and structural study of flaviviridae provides insights into the function and inhibition of HCV helicase
Viral RNA helicases are involved in duplex unwinding during the RNA replication of the virus. It is suggested that these helicases represent very promising antiviral targets. Viruses of the flaviviridae family are the causative agents of many common and devastating diseases, including hepatitis, yel...
Main Authors: | Dimitrios Vlachakis, Vassiliki Lila Koumandou, Sophia Kossida |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2013-05-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/74.pdf |
Similar Items
-
Molecular modeling and pharmacophore elucidation study of the Classical Swine Fever virus helicase as a promising pharmacological target
by: Dimitrios Vlachakis, et al.
Published: (2013-06-01) -
Evolution of the F0F1 ATP synthase complex in light of the patchy distribution of different bioenergetic pathways across prokaryotes.
by: Vassiliki Lila Koumandou, et al.
Published: (2014-09-01) -
Case report: Chronic hepatitis C with anti-HCV positive and serum HCV RNA negative
by: Huihui Lu, et al.
Published: (2023-04-01) -
Structural models for the design of novel antiviral agents against Greek Goat Encephalitis
by: Louis Papageorgiou, et al.
Published: (2014-11-01) -
New Insights on the Glyphosate-Degrading Enzymes C-P Lyase and Glyphosate Oxidoreductase Based on Bioinformatics
by: Marina Giannakara, et al.
Published: (2024-10-01)