Fabrication and In Vitro/Vivo Evaluation of Drug Nanocrystals Self-Stabilized Pickering Emulsion for Oral Delivery of Quercetin

Fabrication and In Vitro/Vivo Evaluation of Drug Nanocrystals Self-Stabilized Pickering Emulsion for Oral Delivery of Quercetin

The aim of this study was to develop a new drug nanocrystals self-stabilized Pickering emulsion (NSSPE) for improving oral bioavailability of quercetin (QT). Quercetin nanocrystal (QT–NC) was fabricated by high pressure homogenization method, and QT–NSSPE was then prepared by ultrasound method with...

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Bibliographic Details
Main Authors: Zhe Wang, Bo Dai, Xiaohan Tang, Zhihui Che, Fei Hu, Chengying Shen, Wei Wu, Baode Shen, Hailong Yuan
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Pharmaceutics
Subjects:
pickering emulsion
self-stabilizing
poorly soluble drug
quercetin
nanocrystals
oral bioavailability
Online Access:https://www.mdpi.com/1999-4923/14/5/897

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