Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells

Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells

Microphthalmia-associated transcription factor (MITF) is the master regulator of the melanocyte lineage. To understand how MITF regulates transcription, we used tandem affinity purification and mass spectrometry to define a comprehensive MITF interactome identifying novel cofactors involved in trans...

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Bibliographic Details
Main Authors: Patrick Laurette, Thomas Strub, Dana Koludrovic, Céline Keime, Stéphanie Le Gras, Hannah Seberg, Eric Van Otterloo, Hana Imrichova, Robert Siddaway, Stein Aerts, Robert A Cornell, Gabrielle Mengus, Irwin Davidson
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-03-01
Series:eLife
Subjects:
chromatin remodelling
SOX10
CHD7
YY1
TFAP2A
enhancer
Online Access:https://elifesciences.org/articles/06857

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