Nitro-Oleic Acid Inhibits Stemness Maintenance and Enhances Neural Differentiation of Mouse Embryonic Stem Cells via STAT3 Signaling

Nitro-Oleic Acid Inhibits Stemness Maintenance and Enhances Neural Differentiation of Mouse Embryonic Stem Cells via STAT3 Signaling

Nitro-oleic acid (NO<sub>2</sub>-OA), pluripotent cell-signaling mediator, was recently described as a modulator of the signal transducer and activator of transcription 3 (STAT3) activity. In our study, we discovered new aspects of NO<sub>2</sub>-OA involvement in the regulat...

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Bibliographic Details
Main Authors: Jana Pereckova, Michaela Pekarova, Nikoletta Szamecova, Zuzana Hoferova, Kristyna Kamarytova, Martin Falk, Tomas Perecko
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
nitro-oleic acid
pluripotency
mouse embryonic stem cells
STAT3
neurogenesis
cardiomyogenesis
Online Access:https://www.mdpi.com/1422-0067/22/18/9981

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