A structure-based approach for detection of thiol oxidoreductases and their catalytic redox-active cysteine residues.

Cysteine (Cys) residues often play critical roles in proteins, for example, in the formation of structural disulfide bonds, metal binding, targeting proteins to the membranes, and various catalytic functions. However, the structural determinants for various Cys functions are not clear. Thiol oxidore...

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Bibliographic Details
Main Authors: Stefano M Marino, Vadim N Gladyshev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2673044?pdf=render